SCHEMBL45616

SCHEMBL45616

O=S(=O)(O)Nc1cccc2ccccc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.67
RECQL P46063 1/20 0.62
ALDH1A1 P00352 5/20 0.56
KDM4E B2RXH2 4/20 0.56
HPGD P15428 3/20 0.56
HSD17B10 Q99714 3/20 0.56
KMT2A Q03164 5/20 0.54
MAPT P10636 5/20 0.54
MEN1 O00255 4/20 0.54
GAA P10253 3/20 0.53
LMNA P02545 2/20 0.49
MCL1 Q07820 1/20 0.49
HTT P42858 1/20 0.49
CYP3A4 P08684 2/20 0.49
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11793189 1.00 KEAP1 (0.67) KEAP1RECQLALDH1A1KDM4EHPGD
SCHEMBL9316866 0.98 KEAP1 (0.65) KEAP1RECQLALDH1A1KDM4EHPGD
SCHEMBL27489988 0.98 KEAP1 (0.65) KEAP1RECQLALDH1A1KDM4EHPGD
SCHEMBL28781311 0.98 KEAP1 (0.65) KEAP1RECQLALDH1A1KDM4EHPGD
SCHEMBL9316618 0.98 KEAP1 (0.65) KEAP1RECQLALDH1A1KDM4EHPGD
Thiosulfuric Acid SCHEMBL7068582 0.94 KEAP1 (0.61) KEAP1RECQLALDH1A1KDM4EHPGD
1-Naphthol SCHEMBL27455138 0.91 KEAP1 (0.57) KEAP1RECQLALDH1A1KDM4EHPGD
Naphthylamine SCHEMBL10704746 0.84 KEAP1 (0.50) KEAP1RECQLALDH1A1KDM4EHPGD
SCHEMBL6005274 0.83 KEAP1 (0.71) KEAP1RECQLALDH1A1KDM4EHPGD
SCHEMBL10780391 0.83 KEAP1 (0.71) KEAP1RECQLALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2552 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024010439-A1 METHOD AND SYSTEM FOR SEPARATING A SOLID AND AT LEAST ONE LIQUID OF A SUSPENSION OCP SA (MA) 2024-01-11 WO claimed
CN-115436333-A Application of tetrazine fluorescence enhanced probe in superoxide anion detection 浙江大学 2022-12-06 CN claimed
CN-111349348-B Reactive dark blue dye and synthetic method thereof 湖北丽源科技股份有限公司 2021-11-23 CN claimed
CN-113004882-A Microemulsion type imbibition agent, preparation method thereof and oil displacement type fracturing fluid system 盘锦鸿鼎油气技术服务有限公司 2021-06-22 CN claimed
CN-107012695-B Penetrating fluid for ink jet textile printing, ink jet textile printing method, and ink jet textile printing apparatus 精工爱普生株式会社 2020-08-07 CN claimed
WO-2020142700-A1 BINDING DOMAIN MAPPING AND COMPOUNDS, COMPOSITIONS, COMPLEXES, METHODS, AND KITS RELATED THERETO George Mason Research Foundation, Inc. (US) 2020-07-09 WO claimed
CN-111349348-A Reactive dark blue dye and synthetic method thereof 湖北丽源科技股份有限公司 2020-06-30 CN claimed
EP-3199603-B1 INK JET PRINTING PENETRANT, INK JET PRINTING METHOD, AND INK JET PRINTING APPARATUS SEIKO EPSON CORP (JP) 2020-04-15 EP claimed
CN-109462982-A Dimension Doreptide under physiological condition with poor solubility is for treating acromegalia, acromegalia cancer, SST-R5 expression type tumour, type-2 diabetes mellitus, hyperglycemia and hormone related neoplasms 斯特朗布里奇都柏林有限公司 2019-03-12 CN claimed
EP-3416666-A1 VELDOREOTIDE WITH POOR SOLUBITLIY IN PHYSIOLOGICAL CONDITIONS FOR USE IN THE TREATMENT OF ACROMEGALY, ACROMEGALY CANCER, SST-R5 EXPRESSING TUMORS, TYPE 2 DIABETES, HYPERGLYCEMIA, AND HORMONE-RELATED TUMORS Strongbridge Ireland Limited (US) 2018-12-26 EP claimed
EP-0053097-A1 Reactive dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1982-06-02 EP claimed
EP-0021837-A1 Metallisable trisazo black dyestuffs and mixtures thereof, their preparation and use in dyeing cellulosic fibres CROMPTON & KNOWLES CORPORATION (US) 1981-01-07 EP claimed
EP-0003583-A1 Compositions for cytochemical investigation, their use and method for the detection of steroid hormone receptors in human tissues Lee, Sin Hang (US) 1979-08-22 EP claimed
EP-0000634-A1 Process for the manufacture of naphthylamine sulphonic acids The Clayton Aniline Company Limited (GB) 1979-02-07 EP claimed
US-4111911-A METHOD OF HARDENING LIQUID RESOLS DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1978-09-05 US claimed
US-4102832-A Method of hardening and foaming liquid resols using a mixture of diluent and aromatic sulfonic acid DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1978-07-25 US claimed
US-4045428-A Water-soluble reactive naphthylazonaphthyl dyestuffs HOECHST AKTIENGESELLSCHAFT (DT) 1977-08-30 US claimed
US-4039523-A YELLOW CIBA-GEIGY AG (CH) 1977-08-02 US claimed
US-3983588-A Process for the dyeing or printing and simultaneous finishing of cellulose materials CIBA-GEIGY AG (CH) 1976-10-05 US claimed
US-3970422-A BASIC DYE TOYO BOSEKI KABUSHIKI KAISHA (JA) 1976-07-20 US claimed