SCHEMBL9316618

SCHEMBL9316618

O=S(=O)(O)Nc1cccc2ccccc12.[Cu]

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.65
RECQL P46063 1/20 0.61
ALDH1A1 P00352 5/20 0.54
KDM4E B2RXH2 4/20 0.54
HPGD P15428 3/20 0.54
HSD17B10 Q99714 3/20 0.54
KMT2A Q03164 5/20 0.53
MAPT P10636 5/20 0.53
MEN1 O00255 4/20 0.53
GAA P10253 3/20 0.52
LMNA P02545 2/20 0.48
MCL1 Q07820 1/20 0.48
HTT P42858 1/20 0.48
CYP3A4 P08684 2/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45616 0.98 KEAP1 (0.67) KEAP1RECQLALDH1A1KDM4EHPGD
SCHEMBL11793189 0.98 KEAP1 (0.67) KEAP1RECQLALDH1A1KDM4EHPGD
SCHEMBL9316866 0.96 KEAP1 (0.65) KEAP1RECQLALDH1A1KDM4EHPGD
SCHEMBL27489988 0.96 KEAP1 (0.65) KEAP1RECQLALDH1A1KDM4EHPGD
SCHEMBL28781311 0.96 KEAP1 (0.65) KEAP1RECQLALDH1A1KDM4EHPGD
Thiosulfuric Acid SCHEMBL7068582 0.93 KEAP1 (0.61) KEAP1RECQLALDH1A1KDM4EHPGD
1-Naphthol SCHEMBL27455138 0.90 KEAP1 (0.57) KEAP1RECQLALDH1A1KDM4EHPGD
Naphthylamine SCHEMBL10704746 0.83 KEAP1 (0.50) KEAP1RECQLALDH1A1KDM4EHPGD
SCHEMBL6005274 0.82 KEAP1 (0.71) KEAP1RECQLALDH1A1KDM4EHPGD
SCHEMBL10780391 0.82 KEAP1 (0.71) KEAP1RECQLALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5236633-A Blend of transparent polymer, thiourea and copper compounds JUJO PAPER CO., LTD. (JP) 1993-08-17 US claimed
US-5354514-A Heating mixture of thioamide compound and copper- or lead-containing compound JUJO PAPER CO., LTD. (JP) 1994-10-11 US disclosed
US-5236633-A Blend of transparent polymer, thiourea and copper compounds JUJO PAPER CO., LTD. (JP) 1993-08-17 US disclosed