Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.47 |
| ▸ | LIMK2 | P53671 | 7/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | RBP4 | P02753 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 2/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2734070 | 0.83 | TRPV1 (0.51) | TRPV1 | |
| SCHEMBL2720307 | 0.81 | TRPV1 (0.42) | TRPV1LIMK2KITPI4KB | |
| SCHEMBL2381414 | 0.80 | TRPV1 (0.54) | TRPV1KIT | |
| SCHEMBL2717524 | 0.80 | TRPV1 (0.42) | TRPV1LIMK2KITPI4KB | |
| SCHEMBL4561718 | 0.78 | TRPV1 (0.48) | TRPV1PDGFRBPDGFRA | |
| SCHEMBL2730160 | 0.78 | TRPV1 (0.45) | TRPV1RBP4PDGFRBPDGFRA | |
| SCHEMBL2717889 | 0.78 | TRPV1 (0.45) | TRPV1 | |
| SCHEMBL2717511 | 0.77 | PI4KB (0.53) | TRPV1LIMK2PI4KB | |
| SCHEMBL2384052 | 0.77 | LIMK2 (0.54) | LIMK2KITPDGFRB | |
| SCHEMBL2385769 | 0.76 | PDGFRB (0.44) | TRPV1LIMK2KITPI4KBPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061337-A1 | FGFR2 MODULATORS | EXELIXIS, INC. (US) | 2012-05-10 | — | — | WO | disclosed |