Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | MALT1 | Q9UDY8 | 13/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2717542 | 0.88 | MALT1 (0.52) | MALT1KDM4EMEN1TSHRKMT2A | |
| SCHEMBL4561882 | 0.83 | TRPV1 (0.47) | TRPV1 | |
| SCHEMBL2720307 | 0.80 | TRPV1 (0.42) | TRPV1MEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL2381414 | 0.79 | TRPV1 (0.54) | TRPV1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL2717524 | 0.79 | TRPV1 (0.42) | TRPV1LMNAHSD17B10L3MBTL1 | |
| SCHEMBL2730160 | 0.78 | TRPV1 (0.45) | TRPV1MEN1KMT2AHSD17B10 | |
| SCHEMBL4561718 | 0.77 | TRPV1 (0.48) | TRPV1LMNAHSD17B10 | |
| SCHEMBL2717889 | 0.77 | TRPV1 (0.45) | TRPV1HSD17B10 | |
| SCHEMBL2717511 | 0.77 | PI4KB (0.53) | TRPV1LMNAHSD17B10 | |
| SCHEMBL2386385 | 0.76 | NPSR1 (0.41) | TRPV1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061337-A1 | FGFR2 MODULATORS | EXELIXIS, INC. (US) | 2012-05-10 | — | — | WO | claimed |
| WO-2012061337-A1 | FGFR2 MODULATORS | EXELIXIS, INC. (US) | 2012-05-10 | — | — | WO | disclosed |