SCHEMBL4562

SCHEMBL4562

O=C1N[C@@H](c2ccccc2)CO1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.42
AR P10275 1/20 0.42
ALDH1A1 P00352 2/20 0.41
CA2 P00918 1/20 0.40
TSHR P16473 1/20 0.40
CYP19A1 P11511 2/20 0.40
KMT2A Q03164 2/20 0.39
LMNA P02545 1/20 0.39
MEN1 O00255 1/20 0.39
BRD4 O60885 1/20 0.38
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
GFER P55789 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL445133 1.00 SMN1; SMN2 (0.42) SMN1; SMN2ARALDH1A1CA2TSHR
SCHEMBL4563 1.00 SMN1; SMN2 (0.42) SMN1; SMN2ARALDH1A1CA2TSHR
SCHEMBL16106147 1.00 SMN1; SMN2 (0.42) SMN1; SMN2ARALDH1A1CA2TSHR
SCHEMBL2909384 0.98 AR (0.41) SMN1; SMN2ARALDH1A1CA2TSHR
SCHEMBL14831166 0.89 TAAR1 (0.41) ARALDH1A1KMT2AMEN1BRD4
SCHEMBL14831167 0.89 TAAR1 (0.41) ARALDH1A1KMT2AMEN1BRD4
SCHEMBL16363903 0.85 KDM4E (0.37) ARALDH1A1CYP19A1KMT2AMEN1
SCHEMBL4532571 0.82 AR (0.41) SMN1; SMN2ARTSHRCYP19A1BRD4
SCHEMBL28983077 0.82 DGAT1 (0.48) SMN1; SMN2ALDH1A1TSHRKMT2ALMNA
SCHEMBL28983075 0.82 DGAT1 (0.48) SMN1; SMN2ALDH1A1TSHRKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1017 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080024-A Cefatigure Synthesis method of An 2026-05-26 CN claimed
CN-120192264-A Preparation method of itramod 深圳市华先医药科技有限公司 2025-06-24 CN claimed
CN-119060991-A Reaction process for preparing (S) -4-phenyl-2-oxazolidinone with high chiral purity and biocatalyst 宁波酶赛生物工程有限公司 2024-12-03 CN claimed
CN-118207195-A Enzymatic preparation of (S) -4-phenyl-2-oxazolidinone and (S) -oxirane 宁波酶赛生物工程有限公司 2024-06-18 CN claimed
CN-117886769-A Synthesis process of S- (+) -4-phenyl-2-oxazolidinone 浙江辰阳化工有限公司 2024-04-16 CN claimed
WO-2024040267-A2 DIRECT SYNTHESIS OF N-(3-SUBSTITUTED-CHROMAN-4-YL)-7H- PYRROLO[2,3-D]PYRIMIDIN-4-AMINES AND DERIVATIVES THEREOF MITOKININ, INC. (US) 2024-02-22 WO claimed
CN-117186150-A Preparation method of LFA-1 inhibitor 维眸生物科技(上海)有限公司 2023-12-08 CN claimed
CN-117038905-A Composite manganese-based positive electrode material, preparation method thereof and lithium ion battery 蜂巢能源科技股份有限公司 2023-11-10 CN claimed
CN-116283948-A Synthesis method of ezetimibe intermediate 江苏阿尔法药业股份有限公司 2023-06-23 CN claimed
CN-112500361-B Preparation method of (S) -4-phenyl-2-oxazolidinone 甘肃瀚聚药业有限公司 2023-05-12 CN claimed
CN-1071745-C Process for the synthesis of azetidinones SCHERING CORP (US) 2001-09-26 CN claimed
EP-0707567-B1 PROCESS FOR THE SYNTHESIS OF AZETIDINONES SCHERING CORP (US) 2001-09-12 EP claimed
US-6207822-B1 REACTING P-FLUOROBENZOYLBUTYRIC ACID WITH PIVALOYL CHLORIDE;ACYLATION; REDUCTION; CYCLIZATION; HYDROSILATION; DEBLOCKING SCHERING CORPORATION 2001-03-27 US claimed
WO-2000034240-A1 PROCESS FOR THE SYNTHESIS OF AZETIDINONES SCHERING CORPORATION (US) 2000-06-15 WO claimed
JP-2840452-B2 1998-12-24 JP claimed
US-5728827-A Process for the synthesis of azetidinones SCHERING CORPORATION (US) 1998-03-17 US claimed
US-5561227-A CHLORINATION A CARBOXYLIC ACID; DEPROTONATION A CHIRAL (OXA OR THIA)ZOLIDINONE; ENOLIZING; CYCLIZATION SCHERING CORPORATION (US) 1996-10-01 US claimed
CN-1126989-A Process for the synthesis of azetidinones SCHERING CORP (US) 1996-07-17 CN claimed
EP-0707567-A1 PROCESS FOR THE SYNTHESIS OF AZETIDINONES SCHERING CORPORATION (US) 1996-04-24 EP claimed
WO-1995001961-A1 PROCESS FOR THE SYNTHESIS OF AZETIDINONES SCHERING CORPORATION (US) 1995-01-19 WO claimed