Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4562 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2ARALDH1A1CA2TSHR | |
| SCHEMBL4563 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2ARALDH1A1CA2TSHR | |
| SCHEMBL16106147 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2ARALDH1A1CA2TSHR | |
| SCHEMBL2909384 | 0.98 | AR (0.41) | SMN1; SMN2ARALDH1A1CA2TSHR | |
| SCHEMBL14831166 | 0.89 | TAAR1 (0.41) | ARALDH1A1KMT2AMEN1BRD4 | |
| SCHEMBL14831167 | 0.89 | TAAR1 (0.41) | ARALDH1A1KMT2AMEN1BRD4 | |
| SCHEMBL16363903 | 0.85 | KDM4E (0.37) | ARALDH1A1CYP19A1KMT2AMEN1 | |
| SCHEMBL4532571 | 0.82 | AR (0.41) | SMN1; SMN2ARTSHRCYP19A1BRD4 | |
| SCHEMBL28983077 | 0.82 | DGAT1 (0.48) | SMN1; SMN2ALDH1A1TSHRKMT2ALMNA | |
| SCHEMBL28983075 | 0.82 | DGAT1 (0.48) | SMN1; SMN2ALDH1A1TSHRKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 843 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117947523-A | Chiral organic-inorganic hybrid lead halide nonlinear frequency doubling crystal | 南开大学 | 2024-04-30 | — | — | CN | claimed |
| CN-114957335-B | Method for preparing chiral metal halide from achiral precursor through chiral induction | 南开大学 | 2024-04-05 | — | — | CN | claimed |
| WO-2024040267-A2 | DIRECT SYNTHESIS OF N-(3-SUBSTITUTED-CHROMAN-4-YL)-7H- PYRROLO[2,3-D]PYRIMIDIN-4-AMINES AND DERIVATIVES THEREOF | MITOKININ, INC. (US) | 2024-02-22 | — | — | WO | claimed |
| CN-115960054-A | Preparation method of ezetimibe intermediate | 南通常佑药业科技有限公司 | 2023-04-14 | — | — | CN | claimed |
| CN-114957335-A | Method for preparing chiral metal halide from achiral precursor by chiral induction | 南开大学 | 2022-08-30 | — | — | CN | claimed |
| CN-114516866-A | Preparation method of chiral 4-alkyl-pyrrole-3-formic acid compound | 南京卓康医药科技有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-109115914-B | High performance liquid chromatography method for separating ramosetron hydrochloride and S-type enantiomer thereof | 四川中科微纳科技有限公司 | 2021-06-04 | — | — | CN | claimed |
| CN-109320441-B | Method for efficiently preparing alkynylamide compound | 江西师范大学 | 2021-01-26 | — | — | CN | claimed |
| WO-2019077627-A1 | A PROCESS FOR THE MANUFACTURE OF POSACONAZOLE | METROCHEM API PVT LTD. (IN) | 2019-04-25 | — | — | WO | claimed |
| US-10093625-B2 | Process for the preparation of [[2(S)-[[4(R)-(3-hydroxyphenyl)-3(R),4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl]amino]acetic acid dihydrate | MSN LABORATORIES PRIVATE LIMITED (IN) | 2018-10-09 | — | — | US | claimed |
| WO-2015059716-A2 | IMPROVED PROCESS FOR THE PREPARATION OF ((3S,5R)-5-((1H-1,2,4-TRIAZOL-1-YL)METHYL)-5-(2,4-DIFLUOROPHENYL)TETRAHYDROFURAN-3-YL)METHYL-4-METHYLBENZENESULFONATE | MSN LABORATORIES PRIVATE LIMITED (IN) | 2015-04-30 | — | — | WO | claimed |
| CN-102477016-B | Synthesis and application of intermediate of tapentadol | INST MATERIA MEDICA CAMS | 2014-12-17 | — | — | CN | claimed |
| US-20140343285-A1 | Process for the Preparation of Triazole Antifungal Drug, Its Intermediates and Polymorphs Thereof | MSN LABORATORIES LIMITED (IN) | 2014-11-20 | — | — | US | claimed |
| EP-2758385-A2 | PROCESS FOR THE PREPARATION OF TRIAZOLE ANTIFUNGAL DRUG, ITS INTERMEDIATES AND POLYMORPHS THEREOF | MSN Laboratories Limited (IN) | 2014-07-30 | — | — | EP | claimed |
| WO-2013042138-A2 | PROCESS FOR THE PREPARATION OF TRIAZOLE ANTIFUNGAL DRUG, ITS INTERMEDIATES AND POLYMORPHS THEREOF | MSN LABORATORIES LIMITED (IN) | 2013-03-28 | — | — | WO | claimed |
| CN-102477016-A | Synthesis and application of intermediate of tapentadol | INST MATERIA MEDICA CAMS | 2012-05-30 | — | — | CN | claimed |
| US-7517876-B2 | Anti-infective agents | ABBOTT LABORATORIES (US) | 2009-04-14 | — | — | US | claimed |
| US-20060287300-A1 | Anti-infective agents | ABBVIE INC. | 2006-12-21 | — | — | US | claimed |
| WO-2006093801-A1 | THIADIAZINE DERIVATIVES USEFUL AS ANTI-INFECTIVE AGENTS | ABBOTT LABORATORIES (US) | 2006-09-08 | — | — | WO | claimed |
| US-6660879-B2 | Use of the compound in clinical conditions associated with insulin resistance. | ASTRAZENECA AB (SE) | 2003-12-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287300-A1 | Anti-infective agents | RPL5, POLI, RPL35 | SMN1; SMN2 4518/4885AR 4825/4885ALDH1A1 2009/4885 |
| US-10093625-B2 | Process for the preparation of [[2(S)-[[4(R)-(3-hydroxyphenyl)-3(R),4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl]amino]acetic acid dihydrate | HPD, HCAR2, GRHPR | SMN1; SMN2 3371/4885AR 604/4885ALDH1A1 6/4885 |
| US-20140343285-A1 | Process for the Preparation of Triazole Antifungal Drug, Its Intermediates and Polymorphs Thereof | CYP3A4, CYP51A1, CYP1B1 | SMN1; SMN2 4425/4885AR 3441/4885ALDH1A1 372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.