Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4562229 | 1.00 | HPGD (0.45) | HPGDLMNAKDM1AMAOAMEN1 | |
| SCHEMBL30595262 | 1.00 | HPGD (0.45) | HPGDLMNAKDM1AMAOAMEN1 | |
| SCHEMBL16670679 | 0.90 | HPGD (0.47) | HPGDLMNAKDM1AMAOAMEN1 | |
| SCHEMBL16682036 | 0.88 | MAPT (0.49) | HPGDLMNAKDM1AMAOAMEN1 | |
| SCHEMBL14556097 | 0.88 | HPGD (0.43) | HPGDLMNAKDM1AMAOAMEN1 | |
| SCHEMBL16682076 | 0.84 | MMP9 (0.46) | HPGDLMNAMEN1KMT2ATAS1R3 | |
| SCHEMBL18041078 | 0.84 | SMN1; SMN2 (0.44) | HPGDLMNAKDM1AMAOAKMT2A | |
| SCHEMBL29679318 | 0.84 | ACE (0.50) | LMNAKDM1AMAOACTSLALDH1A1 | |
| SCHEMBL10204542 | 0.84 | ACE (0.50) | LMNAKDM1AMAOACTSLALDH1A1 | |
| SCHEMBL27010613 | 0.84 | ACE (0.50) | LMNAKDM1AMAOACTSLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065062-A1 | NOVEL ANTIVIRAL COMPOUNDS | PHARMARESOURCES(SHANGHAI)CO., LTD. (CN) | 2012-05-18 | — | — | WO | disclosed |