Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30595262 | 1.00 | HPGD (0.45) | HPGDLMNAKDM1AMAOAMEN1 | |
| SCHEMBL4562228 | 1.00 | HPGD (0.45) | HPGDLMNAKDM1AMAOAMEN1 | |
| SCHEMBL16670679 | 0.90 | HPGD (0.47) | HPGDLMNAKDM1AMAOAMEN1 | |
| SCHEMBL16682036 | 0.88 | MAPT (0.49) | HPGDLMNAKDM1AMAOAMEN1 | |
| SCHEMBL14556097 | 0.88 | HPGD (0.43) | HPGDLMNAKDM1AMAOAMEN1 | |
| SCHEMBL16682076 | 0.84 | MMP9 (0.46) | HPGDLMNAMEN1KMT2ATAS1R3 | |
| SCHEMBL18041078 | 0.84 | SMN1; SMN2 (0.44) | HPGDLMNAKDM1AMAOAKMT2A | |
| SCHEMBL29679318 | 0.84 | ACE (0.50) | LMNAKDM1AMAOACTSLALDH1A1 | |
| SCHEMBL10204542 | 0.84 | ACE (0.50) | LMNAKDM1AMAOACTSLALDH1A1 | |
| SCHEMBL27010613 | 0.84 | ACE (0.50) | LMNAKDM1AMAOACTSLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018139-A1 | NEW SMALL-MOLECULE COMPOUNDS FOR CONTROLLING ENDOSOMAL TOLL-LIKE RECEPTORS AND THERAPEUTIC AGENT FOR AUTOIMMUNE DISEASES USING SAME | S＆K THERAPEUTICS (KR) | 2024-01-18 | — | — | US | disclosed |
| US-20240018139-A1 | NEW SMALL-MOLECULE COMPOUNDS FOR CONTROLLING ENDOSOMAL TOLL-LIKE RECEPTORS AND THERAPEUTIC AGENT FOR AUTOIMMUNE DISEASES USING SAME | S＆K THERAPEUTICS (KR) | 2024-01-18 | — | — | US | disclosed |
| EP-4253382-A1 | NEW SMALL-MOLECULE COMPOUND FOR CONTROLLING ENDOSOMAL TOLL-LIKE RECEPTOR AND THERAPEUTIC AGENT FOR AUTOIMMUNE DISEASES USING SAME | S&K Therapeutics (KR) | 2023-10-04 | — | — | EP | disclosed |
| CN-116507329-A | Novel small molecule compounds for controlling endosomal Toll-like receptor and therapeutic agent for autoimmune disease using the same | S和K 疗法公司 | 2023-07-28 | — | — | CN | disclosed |
| WO-2012065062-A1 | NOVEL ANTIVIRAL COMPOUNDS | PHARMARESOURCES(SHANGHAI)CO., LTD. (CN) | 2012-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018139-A1 | NEW SMALL-MOLECULE COMPOUNDS FOR CONTROLLING ENDOSOMAL TOLL-LIKE RECEPTORS AND THERAPEUTIC AGENT FOR AUTOIMMUNE DISEASES USING SAME | TLR9, TLR8, TLR3 | HPGD 4856/4885LMNA 1737/4885KDM1A 3837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.