Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.44 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5141889 | 0.89 | CNR1 (0.50) | CNR1CNR2KMT2AMEN1HSD11B1 | |
| SCHEMBL4563510 | 0.86 | HSD11B1 (0.40) | CNR1CNR2KMT2AMEN1HSD11B1 | |
| SCHEMBL5141888 | 0.84 | CNR1 (0.53) | CNR1CNR2KMT2AMEN1HPGD | |
| SCHEMBL4563433 | 0.83 | KMT2A (0.50) | CNR1CNR2KMT2AMEN1HSD11B1 | |
| SCHEMBL3683921 | 0.81 | KMT2A (0.52) | CNR1CNR2KMT2AMEN1HSD11B1 | |
| SCHEMBL4562967 | 0.79 | CNR1 (0.44) | CNR1CNR2KMT2AMEN1POLB | |
| SCHEMBL4562966 | 0.71 | KMT2A (0.49) | CNR1CNR2KMT2AMEN1HSD11B1 | |
| SCHEMBL4563366 | 0.70 | KMT2A (0.54) | CNR1CNR2KMT2AMEN1HSD11B1 | |
| SCHEMBL4563605 | 0.69 | KMT2A (0.47) | CNR1CNR2KMT2AMEN1HSD11B1 | |
| SCHEMBL5363741 | 0.67 | KDM4E (0.55) | CNR1CNR2KMT2AMEN1CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026798-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING CBX CANNABINOID RECEPTOR MODULATORS AND POTASSIUM CHANNEL MODULATORS | Solvay Pharmaceuticals GmbH (DE) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007125048-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING CBX CANNABINOID RECEPTOR MODULATORS AND POTASSIUM CHANNEL MODULATORS | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-11-08 | — | — | WO | disclosed |