⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18799894 | 0.78 | — | — | |
| SCHEMBL18799910 | 0.76 | — | — | |
| SCHEMBL18912228 | 0.69 | KDM4E (0.41) | — | |
| SCHEMBL18912225 | 0.69 | ALDH1A1 (0.39) | — | |
| SCHEMBL2845116 | 0.69 | GLS (0.64) | — | |
| SCHEMBL147208 | 0.69 | — | — | |
| SCHEMBL4758840 | 0.69 | KDM4E (0.43) | — | |
| Lithium Ion SCHEMBL4758839 | 0.67 | KDM4E (0.42) | — | |
| SCHEMBL6742811 | 0.67 | — | — | |
| SCHEMBL22340515 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107658-A2 | INHIBITORS OF TYK2 | VYRNWY THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| US-20230242548-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-08-03 | — | — | US | disclosed |
| CN-116413344-A | Quality control method and application of reagent | 药源药物化学（上海）有限公司 | 2023-07-11 | — | — | CN | disclosed |
| US-20220223825-A1 | LAMINATE AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2022-07-14 | — | — | US | disclosed |
| EP-3359154-B1 | WNT SIGNALING PATHWAY INHIBITORS AND THERAPEUTIC APPLICATIONS THEREOF | Suzhou Yunxuan Yiyao Keji Youxian Gongsi (CN) | 2021-05-26 | — | — | EP | disclosed |
| EP-3221295-B1 | MONOCARBOXYLATE TRANSPORT MODULATORS AND USES THEREOF | NIROGY THERAPEUTICS INC (US) | 2021-04-14 | — | — | EP | disclosed |
| WO-2017088755-A1 | AMINOPYRIMIDINE HETEROCYCLIC COMPOUND WITH ADENOSINE RECEPTOR ANTAGONISTIC ACTIVITY | Suzhou Yunxuan Yiyao Keji Youxian Gongsi (CN) | 2017-06-01 | — | — | WO | disclosed |
| WO-2017040451-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-03-09 | — | — | WO | disclosed |
| WO-2014078813-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | IRM LLC (BM) | 2014-05-22 | — | — | WO | disclosed |
| EP-2131655-A2 | TRI-ARYL/HETEROAROMATIC CANNABINOIDS AND USE THEREOF | The University of Tennessee Research Foundation (US) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008109027-A2 | TRI-ARYL/HETEROAROAROMATIC CANNABINOIDS AND USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2008-09-12 | — | — | WO | disclosed |