Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4563180 | 0.89 | — | — | |
| SCHEMBL4304109 | 0.85 | THRB (0.34) | — | |
| SCHEMBL4304033 | 0.85 | THRB (0.34) | — | |
| SCHEMBL4302453 | 0.84 | THRA (0.37) | — | |
| SCHEMBL4295203 | 0.71 | THRB (0.34) | — | |
| SCHEMBL4299991 | 0.71 | CHEK2 (0.43) | — | |
| SCHEMBL4299290 | 0.70 | THRA (0.36) | — | |
| SCHEMBL3981706 | 0.70 | THRA (0.39) | — | |
| SCHEMBL4297760 | 0.70 | THRB (0.37) | — | |
| SCHEMBL3985944 | 0.70 | THRA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024336-A1 | NOVEL PHARMACEUTICAL COMPOSITIONS | KARO BIO AB (SE) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007128492-A1 | NOVEL PHARMACEUTICAL COMPOSITIONS | KARO BIO AB (SE) | 2007-11-15 | — | — | WO | disclosed |