Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4563987 | 0.87 | TSHR (0.32) | TSHRTP53 | |
| SCHEMBL1012200 | 0.85 | ADORA2A (0.36) | GAATP53 | |
| SCHEMBL1396811 | 0.84 | KDM4E (0.36) | GAAIRAK4 | |
| SCHEMBL2248952 | 0.80 | TSHR (0.47) | TSHRGAAIRAK4TP53 | |
| SCHEMBL3118115 | 0.78 | ALDH1A1 (0.34) | TSHR | |
| SCHEMBL27774048 | 0.77 | HIF1A (0.37) | GAAIRAK4 | |
| SCHEMBL1136291 | 0.77 | GAA (0.31) | GAAIRAK4 | |
| SCHEMBL27753360 | 0.77 | CYP4F2 (0.34) | TSHRGAAIRAK4 | |
| SCHEMBL2576002 | 0.76 | IRAK4 (0.33) | GAAIRAK4 | |
| SCHEMBL1135830 | 0.76 | IRAK4 (0.33) | GAAIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121618-A1 | PROCESS FOR PREPARING FLUOROMETHYL-SUBSTITUTED HETEROCYCLIC COMPOUNDS | BASF SE (DE) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008077907-A1 | PROCESS FOR PREPARING FLUOROMETHYL-SUBSTITUTED HETEROCYCLIC COMPOUNDS | BASF SE (DE) | 2008-07-03 | — | — | WO | disclosed |