Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | GLA | P06280 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439677 | 0.94 | TSHR (0.38) | TSHRTP53GAAKDM4EHPGD | |
| SCHEMBL28363345 | 0.87 | ALDH1A1 (0.36) | TSHRGAAKDM4EGLAHPGD | |
| SCHEMBL21126224 | 0.87 | TSHR (0.42) | TSHRTP53KDM4EHPGDALDH1A1 | |
| SCHEMBL2251889 | 0.86 | TSHR (0.47) | TSHRTP53GAAKDM4EGLA | |
| SCHEMBL28359952 | 0.84 | LMNA (0.47) | TSHRALDH1A1 | |
| SCHEMBL15280688 | 0.84 | CYP11B1 (0.32) | TSHRGAAACACB | |
| SCHEMBL19186 | 0.84 | JMJD6 (0.44) | TSHRTP53GAAKDM4EGLA | |
| SCHEMBL596089 | 0.83 | GAA (0.40) | GAAGLAALDH1A1HSD17B10ACACB | |
| SCHEMBL28359954 | 0.83 | TSHR (0.42) | TSHRTP53KDM4EALDH1A1CASP1 | |
| SCHEMBL4563231 | 0.80 | TSHR (0.32) | TSHRTP53GAAIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994207-B2 | Process for preparing fluoromethyl-substituted heterocyclic compounds | BASF SE (DE) | 2011-08-09 | — | — | US | disclosed |
| US-20100022782-A1 | Process for Preparing Fluoromethyl-Substituted Heterocyclic Compounds | BASF SE (DE) | 2010-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022782-A1 | Process for Preparing Fluoromethyl-Substituted Heterocyclic Compounds | AFF4, AFF1, F12 | TSHR 1557/4885TP53 2320/4885GAA 1921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.