Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065635 | 0.91 | MCHR1 (0.51) | HPGDMCHR1ACHEHSD17B3DRD2 | |
| SCHEMBL12896004 | 0.83 | ASIC3 (0.49) | ASIC3PLAUDRD2DRD3F2 | |
| SCHEMBL3297638 | 0.82 | MELK (0.49) | — | |
| Hydrochloric Acid SCHEMBL3291961 | 0.81 | MELK (0.48) | — | |
| SCHEMBL1013707 | 0.80 | NPC1 (0.53) | ASIC3PLAUDRD2DRD3F2 | |
| Hydrochloric Acid SCHEMBL3118453 | 0.78 | NPC1 (0.51) | ASIC3PLAUDRD2DRD3F2 | |
| SCHEMBL31532288 | 0.78 | CA12 (0.49) | — | |
| SCHEMBL1019877 | 0.78 | CA12 (0.49) | — | |
| SCHEMBL1026101 | 0.78 | ALDH1A1 (0.59) | ASIC3PLAUDRD2DRD3F2 | |
| SCHEMBL30428318 | 0.78 | ALDH1A1 (0.59) | ASIC3PLAUDRD2DRD3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114890-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008097428-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2008-08-14 | — | — | WO | disclosed |