Bemotrizinol

Bemotrizinol

SCHEMBL4563326

CCCCC(CC)COc1ccc(-c2nc(-c3ccc(OC)cc3)nc(-c3ccc(OCC(CC)CCCC)cc3O)n2)c(O)c1.CCCCCc1nc(CCCCC)nc(-c2ccccc2O)n1

nearest known ligand 0.36

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.36
MEN1 O00255 5/20 0.35
KMT2A Q03164 5/20 0.35
ATM Q13315 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
MAPT P10636 7/20 0.35
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
GPR35 Q9HC97 1/20 0.35
GPR55 Q9Y2T6 1/20 0.35
NPSR1 Q6W5P4 2/20 0.35
POLB P06746 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
NPC1 O15118 3/20 0.34
HTT P42858 2/20 0.34
RAB9A P51151 2/20 0.34
ALDH1A1 P00352 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ALOX15 P16050 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bemotrizinol SCHEMBL77320 0.88 TDP1 (0.43) LMNAMEN1KMT2ATDP1MAPT
Bemotrizinol SCHEMBL29360093 0.88 TDP1 (0.43) LMNAMEN1KMT2ATDP1MAPT
SCHEMBL10195000 0.88 TDP1 (0.43) LMNAMEN1KMT2ATDP1MAPT
Bemotrizinol SCHEMBL29350308 0.88 TDP1 (0.43) LMNAMEN1KMT2ATDP1MAPT
SCHEMBL22854980 0.87 TDP1 (0.42) LMNAMEN1KMT2ATDP1MAPT
Bemotrizinol SCHEMBL26987980 0.86 TDP1 (0.39) LMNAMEN1KMT2ATDP1MAPT
SCHEMBL20024334 0.85 CNR1 (0.41) LMNAMEN1KMT2ATDP1MAPT
SCHEMBL7057519 0.85 LMNA (0.41) LMNAMEN1KMT2AATMTDP1
Bemotrizinol SCHEMBL7526147 0.84 TDP1 (0.38) LMNAMEN1KMT2ATDP1MAPT
SCHEMBL12877715 0.84 TDP1 (0.39) LMNAMEN1KMT2ATDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7608383-B2 UV radiation blocking protective layers compatible with thick film pastes E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-10-27 US disclosed
US-20080274430-A1 UV RADIATION BLOCKING PROTECTIVE LAYERS COMPATIBLE WITH THICK FILM PASTES KIM YOUNG H 2008-11-06 US disclosed
US-7402373-B2 UV radiation blocking protective layers compatible with thick film pastes E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-22 US disclosed
EP-1714189-A2 UV RADIATION BLOCKING PROTECTIVE LAYERS COMPATIBLE WITH THICK FILM PASTES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-10-25 EP disclosed
US-20050227168-A1 UV radiation blocking protective layers compatible with thick film pastes E. I. DU PONT DE NEMOURS AND COMPANY 2005-10-13 US disclosed
WO-2005077032-A2 UV RADIATION BLOCKING PROTECTIVE LAYERS COMPATIBLE WITH THICK FILM PASTES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-08-25 WO disclosed