Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093852 | 0.89 | NPC1 (0.40) | LMNAMEN1KMT2AATMTDP1 | |
| SCHEMBL28678998 | 0.88 | LMNA (0.38) | LMNAMEN1KMT2AATMTDP1 | |
| SCHEMBL31453286 | 0.87 | LMNA (0.49) | LMNAMEN1KMT2AATMTDP1 | |
| SCHEMBL24431551 | 0.87 | LMNA (0.40) | LMNAMEN1KMT2AATMTDP1 | |
| SCHEMBL10195000 | 0.85 | TDP1 (0.43) | LMNAMEN1KMT2ATDP1MAPT | |
| Bemotrizinol SCHEMBL77320 | 0.85 | TDP1 (0.43) | LMNAMEN1KMT2ATDP1MAPT | |
| Bemotrizinol SCHEMBL29350308 | 0.85 | TDP1 (0.43) | LMNAMEN1KMT2ATDP1MAPT | |
| Bemotrizinol SCHEMBL29360093 | 0.85 | TDP1 (0.43) | LMNAMEN1KMT2ATDP1MAPT | |
| SCHEMBL29354615 | 0.85 | LMNA (0.36) | LMNAMEN1KMT2AATMTDP1 | |
| Bemotrizinol SCHEMBL4563326 | 0.85 | LMNA (0.36) | LMNAMEN1KMT2AATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1306081-A1 | Cosmetic use of DHEA-derivatives | L'OREAL (FR) | 2003-05-02 | — | — | EP | disclosed |