Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456990 | 0.72 | TNF (0.46) | ERN1MAPK1 | |
| SCHEMBL470155 | 0.72 | TNF (0.46) | ERN1MAPK1 | |
| SCHEMBL458151 | 0.72 | ERN1 (0.33) | ERN1 | |
| SCHEMBL455120 | 0.72 | TTK (0.36) | ERN1 | |
| SCHEMBL456397 | 0.72 | TNF (0.43) | ERN1MAPK1 | |
| SCHEMBL31285448 | 0.71 | TYK2 (0.34) | ERN1 | |
| SCHEMBL457308 | 0.71 | ERN1 (0.33) | ERN1 | |
| SCHEMBL455915 | 0.70 | SCN5A (0.42) | ERN1 | |
| SCHEMBL469895 | 0.69 | ERN1 (0.43) | ERN1 | |
| SCHEMBL457647 | 0.69 | ERN1 (0.43) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9255100-B2 | Substituted imidazopyridazines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-09 | — | — | US | disclosed |
| EP-2614063-B1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER IP GMBH (DE) | 2016-01-13 | — | — | EP | disclosed |
| EP-2614063-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | Bayer Intellectual Property GmbH (DE) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |