⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL263483 | 0.83 | — | — | |
| SCHEMBL1717354 | 0.80 | TSHR (0.38) | — | |
| SCHEMBL35672 | 0.76 | — | — | |
| SCHEMBL8853811 | 0.76 | HCAR2 (0.34) | — | |
| SCHEMBL7179281 | 0.76 | HCAR2 (0.34) | — | |
| SCHEMBL5838713 | 0.75 | TSHR (0.34) | — | |
| SCHEMBL8984921 | 0.74 | LMNA (0.33) | — | |
| SCHEMBL16723291 | 0.74 | — | — | |
| SCHEMBL65879 | 0.73 | TSHR (0.35) | — | |
| SCHEMBL5838035 | 0.73 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994015980-A1 | NOVEL MACROMONOMERS | BAUSCH & LOMB INCORPORATED (US) | 1994-07-21 | — | — | WO | claimed |
| WO-2009085642-A1 | TRIMETHYLSILYL-CAPPED POLYSILOXANE MACROMONOMERS CONTAINING POLAR FLUORINATED SIDE-CHAINS | BAUSCH & LOMB INCORPORATED (US) | 2009-07-09 | — | — | WO | disclosed |