SCHEMBL65879

SCHEMBL65879

C=C(C)C(=O)OC(CC)[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.35
ALDH1A1 P00352 2/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9418352 0.94 TSHR (0.32) TSHRTHRB
SCHEMBL8167214 0.92 TSHR (0.33) TSHRALDH1A1THRB
SCHEMBL4972445 0.92 TSHR (0.33) TSHRALDH1A1THRB
SCHEMBL5837859 0.92 TSHR (0.33) TSHRALDH1A1THRB
Glycerin SCHEMBL2138419 0.91 TSHR (0.30) TSHR
SCHEMBL4884446 0.90 TSHR (0.32) TSHR
Tromethamine SCHEMBL1969065 0.89
SCHEMBL4738203 0.86 TSHR (0.35) TSHRALDH1A1THRB
SCHEMBL1273966 0.86 TSHR (0.35) TSHRALDH1A1THRB
SCHEMBL10941021 0.86 TSHR (0.35) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3050 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132232-A1 OPHTHALMIC DEVICES BAUSCH LOMB IRELAND LTD (IE) 2026-05-14 US claimed
US-12600820-B2 Photocurable composition with high silicon content CANON KABUSHIKI KAISHA (JP) 2026-04-14 US claimed
WO-2026041842-A1 PACKAGED AND AUTOCLAVED SILICONE HYDROGEL CONTACT LENS WITH HYDROXYALKYL CELLULOSE COOPERVISION INTERNATIONAL LIMITED (GB) 2026-02-26 WO claimed
US-20260055342-A1 PACKAGED CONTACT LENS COOPERVISION INTERNATIONAL LIMITED (GB) 2026-02-26 US claimed
US-20260042269-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US claimed
US-20260042268-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US claimed
US-20250368802-A1 PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT AND HIGH STABILITY CANON KK (JP) 2025-12-04 US claimed
EP-4657144-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
EP-4657145-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
EP-3426703-B1 IMPROVED HYDROPHILIC COMPOSITIONS SUPERDIELECTRICS SUPERCAP LTD (GB) 2025-09-03 EP claimed
US-5023159-A Encapsulated electrophotographic toner compositions XEROX CORPORATION (US) 1991-06-11 US claimed
EP-0406161-A2 Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof CIBA-GEIGY AG (CH) 1991-01-02 EP claimed
EP-0401990-A2 Prepolymers useful in biomedical devices BAUSCH & LOMB INCORPORATED (US) 1990-12-12 EP claimed
EP-0277771-A2 Continuous-wear lenses having improved physical properties BAUSCH & LOMB INCORPORATED (US) 1988-08-10 EP claimed
US-4661573-A INTRAOCULAR AND CONTACT LENSES; COPOLYMER OF PERFLUROALKYL ACRYLATE, ACRYLOXYALKYLPOLYSILOXANE, ACRYLOXYALKYLSILANOL, POLYACRYLOXYALKYLPOLYSILOXANE PARAGON OPTICAL INC. (US) 1987-04-28 US claimed
US-4543398-A Ophthalmic devices fabricated from urethane acrylates of polysiloxane alcohols MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-09-24 US claimed
US-4508884-A COPOLYMER OF UNSATURATED SILICONE ESTER, UNSATURATED ESTER, HYDROP COOPERVISION, INC. (US) 1985-04-02 US claimed
US-4500695-A Silicone-vinyl acetate composition for contact lenses IVANI EDWARD J 1985-02-19 US claimed
EP-0127321-A1 Ophthalmic devices fabricated from urethane acrylates of polysiloxane alcohols MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-12-05 EP claimed
US-4410674-A Silicone-vinyl acetate composition for contact lenses IVANI EDWARD J 1983-10-18 US claimed