Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | GALR3 | O60755 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1879407 | 0.82 | TLR8 (0.66) | TLR8POLBALDH1A1KMT2AHTT | |
| SCHEMBL11531858 | 0.82 | TLR8 (0.66) | TLR8POLBALDH1A1KMT2AHTT | |
| SCHEMBL902006 | 0.82 | TLR8 (0.66) | TLR8POLBALDH1A1KMT2AHTT | |
| SCHEMBL6889380 | 0.82 | TLR8 (0.66) | TLR8POLBALDH1A1KMT2AHTT | |
| SCHEMBL4230750 | 0.82 | TLR8 (0.66) | TLR8POLBALDH1A1KMT2AHTT | |
| SCHEMBL902477 | 0.80 | TLR8 (0.59) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL5286463 | 0.80 | TLR8 (0.59) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL11569500 | 0.80 | TLR8 (0.59) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL5303316 | 0.80 | TLR8 (0.59) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL11533777 | 0.80 | TLR8 (0.59) | TLR8POLBALDH1A1KMT2ATBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146146-A2 | NOVEL IONIC LIQUIDS, FUNCTIONALIZED PARTICULATES, AND FLUOROPOLYMER COMPOSITES | HSIAO BENJAMIN S (US) | 2009-12-03 | — | — | WO | disclosed |