Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 4/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3595758 | 0.90 | DRD2 (0.41) | LMNAHTTMAPTCETPHTR1A | |
| SCHEMBL3677797 | 0.90 | CNR1 (0.42) | LMNAHTTMAPTCETPDRD2 | |
| SCHEMBL3593525 | 0.89 | DRD2 (0.48) | LMNAHTTMAPTCETPDRD2 | |
| SCHEMBL15170649 | 0.89 | CETP (0.37) | LMNAHTTMAPTCETPHTR1A | |
| SCHEMBL3593742 | 0.89 | P2RX7 (0.40) | CETPHTR1ADRD2DRD3LTA4H | |
| SCHEMBL3585947 | 0.88 | CETP (0.40) | LMNAHTTMAPTCETPHTR1A | |
| SCHEMBL3594738 | 0.87 | CETP (0.38) | LMNAHTTMAPTCETPHTR1A | |
| SCHEMBL3594261 | 0.86 | CETP (0.47) | LMNAHTTMAPTCETPKMT2A | |
| SCHEMBL3591074 | 0.86 | CETP (0.45) | LMNAHTTMAPTCETPKMT2A | |
| SCHEMBL3588823 | 0.85 | P2RX7 (0.42) | CETPLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | disclosed |