Triaziquone

Triaziquone

SCHEMBL4564293

Cc1ccnc2cccc(O)c12.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1.[AlH3]

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
HIF1A Q16665 1/20 0.38
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.35
ALOX15 P16050 1/20 0.35
ELANE P08246 2/20 0.33
DNMT1 P26358 1/20 0.32
PARP1 P09874 1/20 0.31
TP53 P04637 1/20 0.31
STAT3 P40763 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PREP P48147 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL327208 0.83 HTT (0.44) CYP1A2CYP3A4CYP2D6TSHRMAPK1
Triaziquone SCHEMBL3240330 0.80 TSHR (0.42) CYP1A2CYP3A4CYP2D6TSHRMAPK1
Triaziquone SCHEMBL7716307 0.79 CYP3A4 (0.44) CYP1A2CYP3A4CYP2D6TSHRMAPK1
Triaziquone SCHEMBL3414962 0.77 DNMT1 (0.44) CYP1A2CYP3A4CYP2D6TSHRMAPK1
Triaziquone SCHEMBL3275757 0.76 CYP1A2 (0.35) CYP1A2CYP3A4CYP2D6TSHRMAPK1
Triaziquone SCHEMBL3874264 0.75 DNMT1 (0.44) CYP1A2CYP3A4CYP2D6TSHRMAPK1
SCHEMBL5539377 0.74 MAPT (0.43) TSHRMAPK1MAPTKDM4EGAA
Triaziquone SCHEMBL312861 0.74 KDM4E (0.52) CYP1A2CYP3A4CYP2D6TSHRMAPK1
Triaziquone SCHEMBL1991925 0.74 KDM4E (0.52) CYP1A2CYP3A4CYP2D6TSHRMAPK1
Triaziquone SCHEMBL1194235 0.74 HTT (0.57) CYP1A2CYP3A4CYP2D6TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8310147-B2 Luminescent device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-11-13 US disclosed
US-20090273280-A1 LUMINESCENT DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-11-05 US disclosed