Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triaziquone SCHEMBL3414962 | 0.83 | DNMT1 (0.44) | DNMT1CYP3A4TSHRCYP1A2MAPK1 | |
| Triaziquone SCHEMBL8303 | 0.82 | DNMT1 (0.48) | DNMT1CYP3A4TSHRCYP1A2MAPK1 | |
| Triaziquone SCHEMBL7116771 | 0.81 | DNMT1 (0.43) | DNMT1CYP3A4TSHRCYP1A2MAPK1 | |
| Triaziquone SCHEMBL4961328 | 0.81 | CA2 (0.47) | DNMT1CYP3A4TSHRCYP1A2MAPK1 | |
| Triaziquone SCHEMBL7783197 | 0.81 | MAPT (0.46) | DNMT1CYP3A4TSHRCYP1A2MAPK1 | |
| Triaziquone SCHEMBL10904679 | 0.81 | DNMT1 (0.47) | DNMT1CYP3A4TSHRCYP1A2MAPK1 | |
| Triaziquone SCHEMBL3462769 | 0.81 | DNMT1 (0.47) | DNMT1CYP3A4TSHRCYP1A2MAPK1 | |
| Triaziquone SCHEMBL8993238 | 0.80 | DNMT1 (0.47) | DNMT1CYP3A4TSHRCYP1A2MAPK1 | |
| Triaziquone SCHEMBL6000230 | 0.80 | DNMT1 (0.47) | DNMT1CYP3A4TSHRCYP1A2MAPK1 | |
| Triaziquone SCHEMBL1538515 | 0.80 | DNMT1 (0.47) | DNMT1CYP3A4TSHRCYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1483577-B1 | ABSORBING ORGANIC REAGENTS INTO DIAGNOSTIC TEST DEVICES BY FORMATION OF AMINE SALT COMPLEXES | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2015-01-07 | — | — | EP | disclosed |
| US-7563621-B2 | Absorbing organic reagents into diagnostic test devices by formation of amine salt complexes | Siemens Healhcare Diagnostics Inc (US) | 2009-07-21 | — | — | US | disclosed |
| US-20050106748-A1 | Absorbing organic reagent into diagnostic test devices by formation of amine salt complexes | SIEMENS HEALTHCARE DIAGNOSTICS INC. | 2005-05-19 | — | — | US | disclosed |