Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 13/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | F9 | P00740 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15889924 | 0.84 | NOTUM (0.63) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL30413228 | 0.84 | NOTUM (0.63) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL4482463 | 0.81 | NOTUM (0.54) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL16787394 | 0.79 | NOTUM (0.58) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL13735664 | 0.79 | NOTUM (0.58) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL18016687 | 0.78 | NOTUM (0.51) | NOTUMKEAP1CYP19A1TDP1 | |
| SCHEMBL20437909 | 0.77 | NOTUM (0.58) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL13629601 | 0.77 | NOTUM (0.58) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL4557446 | 0.76 | CYP19A1 (0.48) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL15520028 | 0.76 | NOTUM (0.50) | NOTUMKEAP1CYP19A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010495-A2 | NEW HYDROXYPHENYL DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF | Mutabilis SA (FR) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007135562-A2 | HYDROXYPHENYL DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF | MUTABILIS S.A. (FR) | 2007-11-29 | — | — | WO | disclosed |