Propionaldehyde

Propionaldehyde

SCHEMBL4564734

CCC=O.CCCCc1ccccc1CCC=O.O=[PH2]O

nearest known ligand 0.40

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
LIPG Q9Y5X9 1/20 0.39
THRA P10827 1/20 0.37
THRB P10828 1/20 0.37
BID P55957 3/20 0.35
BCL2L1 Q07817 3/20 0.35
MCL1 Q07820 3/20 0.35
BAK1 Q16611 3/20 0.35
MMP2 P08253 2/20 0.35
F7 P08709 2/20 0.35
F3 P13726 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
ALOX15 P16050 1/20 0.35
ECE1 P42892 1/20 0.35
SGMS1 Q86VZ5 1/20 0.35
SGMS2 Q8NHU3 1/20 0.35
MUS81 Q96NY9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionaldehyde SCHEMBL29282081 0.92 CYP3A4 (0.41) CYP3A4CYP2D6CYP2C9LIPGTHRA
Propionaldehyde SCHEMBL4564022 0.90 PPARG (0.33) LIPG
Propionaldehyde SCHEMBL4564588 0.89 GABRA1 (0.35)
SCHEMBL30845912 0.88 TSHR (0.44) CYP3A4CYP2D6CYP2C9LIPGTHRA
SCHEMBL3345733 0.88 TSHR (0.44) CYP3A4CYP2D6CYP2C9LIPGTHRA
Butanal SCHEMBL4564980 0.88 CYP3A4 (0.40) CYP3A4CYP2D6CYP2C9LIPGTHRA
SCHEMBL3693829 0.83 LIPG (0.50) LIPGTHRATHRBBIDBCL2L1
Propionaldehyde SCHEMBL4563938 0.83 TAAR1 (0.42) MAPT
SCHEMBL28437315 0.82 LIPG (0.53) LIPGTHRATHRBBIDBCL2L1
SCHEMBL96898 0.81 TSHR (0.50) CYP3A4CYP2D6CYP2C9LIPGTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed