SCHEMBL4564753

SCHEMBL4564753

CC(=C(O)C(=O)O)c1ccccc1C

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ERCC5 P28715 1/20 0.52
FEN1 P39748 1/20 0.52
HPGD P15428 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.44
MYC P01106 1/20 0.44
ALDH1A1 P00352 3/20 0.44
KDM4E B2RXH2 2/20 0.44
HSD17B10 Q99714 2/20 0.44
KMT2A Q03164 2/20 0.43
HTT P42858 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
GAA P10253 1/20 0.41
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9364531 0.83 ERCC5 (0.52) ERCC5FEN1HPGDSMN1; SMN2MYC
SCHEMBL5542486 0.83 ERCC5 (0.52) ERCC5FEN1HPGDSMN1; SMN2MYC
SCHEMBL29475720 0.80 ERCC5 (0.49) ERCC5FEN1HPGDSMN1; SMN2MYC
SCHEMBL16329878 0.78 HPGD (0.45) ERCC5FEN1HPGDSMN1; SMN2MYC
SCHEMBL166031 0.76 ERCC5 (0.57) ERCC5FEN1HPGDSMN1; SMN2MYC
SCHEMBL9711362 0.76 ERCC5 (0.57) ERCC5FEN1HPGDSMN1; SMN2MYC
Toluic Acid SCHEMBL27709480 0.76 ALDH1A1 (0.59) ERCC5FEN1HPGDSMN1; SMN2MYC
SCHEMBL20564513 0.76 ERCC5 (0.57) ERCC5FEN1HPGDSMN1; SMN2MYC
Toluic Acid SCHEMBL28576866 0.76 ALDH1A1 (0.59) ERCC5FEN1HPGDSMN1; SMN2MYC
SCHEMBL112406 0.75 HPGD (0.57) ERCC5FEN1HPGDSMN1; SMN2MYC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2049577-A2 METHODS FOR PREPARING POLYMERS FROM PHENOLIC MATERIALS AND COMPOSITIONS RELATING THERETO Dupont Electronic Polymers L.P. (US) 2009-04-22 EP claimed
WO-2008016496-A2 METHODS FOR PREPARING POLYMERS FROM PHENOLIC MATERIALS AND COMPOSITIONS RELATING THERETO DUPONT ELECTRONIC POLYMERS L.P. (US) 2008-02-07 WO claimed