Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.57 |
| ▸ | FEN1 | P39748 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MYC | P01106 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166031 | 1.00 | ERCC5 (0.57) | ERCC5FEN1HPGDPOLBCYP2C19 | |
| Dimethylamine SCHEMBL3965554 | 0.94 | ERCC5 (0.56) | ERCC5FEN1HPGDPOLBCYP2C19 | |
| Benzoyl Formic Acid SCHEMBL4889317 | 0.92 | CES2 (0.50) | ERCC5FEN1HPGDPOLBCYP2C19 | |
| SCHEMBL166603 | 0.87 | HPGD (0.54) | ERCC5FEN1HPGDPOLBMYC | |
| SCHEMBL29425530 | 0.87 | HPGD (0.54) | ERCC5FEN1HPGDPOLBMYC | |
| Methyl Benzoate SCHEMBL30404125 | 0.84 | TSHR (0.63) | ERCC5FEN1HPGDALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL9391088 | 0.83 | HPGD (0.50) | ERCC5FEN1HPGDPOLBMYC | |
| SCHEMBL29089128 | 0.83 | HPGD (0.50) | ERCC5FEN1HPGDPOLBMYC | |
| SCHEMBL8104638 | 0.83 | ERCC5 (0.50) | ERCC5FEN1HPGDMYCKDM4E | |
| SCHEMBL3627482 | 0.82 | CES2 (0.61) | ERCC5FEN1HPGDALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018116-A1 | COMPOSITIONS COMPRISING 2-HYDROXYCARBOXYLIC ACIDS AND RELATED COMPOUNDS, AND METHODS FOR ALLEVIATING SIGNS OF DERMATOLOGICAL AGING | YU RUEY J (US) | 1992-10-29 | — | — | WO | disclosed |