Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6028262 | 0.71 | TSHR (0.31) | — | |
| SCHEMBL9829066 | 0.69 | EPHX1 (0.41) | KDM4CEPHX1 | |
| SCHEMBL9829061 | 0.68 | ALDH1A1 (0.47) | KDM4CNAALAD2 | |
| SCHEMBL9829055 | 0.68 | ALDH1A1 (0.47) | KDM4CNAALAD2 | |
| SCHEMBL6027948 | 0.67 | EPHX1 (0.36) | EPHX1 | |
| SCHEMBL9828329 | 0.66 | HRH3 (0.54) | — | |
| SCHEMBL9828332 | 0.66 | HRH3 (0.54) | — | |
| SCHEMBL10207220 | 0.65 | TSHR (0.39) | KDM4CNAALAD2 | |
| SCHEMBL20999124 | 0.65 | TSHR (0.39) | KDM4CNAALAD2 | |
| SCHEMBL22487748 | 0.65 | TSHR (0.39) | KDM4CNAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120652-A2 | MONOCYCLIC CGRP RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2009-10-01 | — | — | WO | disclosed |