Depreotide

Depreotide

SCHEMBL456503

CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccccc2)N(C)C(=O)[C@H](CCSCC(=O)NC[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(N)=O)NC1=O

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SSTR5 P35346 17/20 0.79
SSTR2 P30874 16/20 0.79
SSTR3 P32745 11/20 0.79
SSTR4 P31391 10/20 0.79
SSTR1 P30872 10/20 0.79
DRD2 P14416 2/20 0.44
IL23R Q5VWK5 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Depreotide SCHEMBL29399302 1.00 SSTR5 (0.79) SSTR5SSTR2SSTR3SSTR4SSTR1
Depreotide SCHEMBL17136142 0.97 SSTR5 (0.76) SSTR5SSTR2SSTR3SSTR4SSTR1
Depreotide SCHEMBL29392879 0.87 SSTR5 (0.62) SSTR5SSTR2SSTR3SSTR4SSTR1
SCHEMBL24108700 0.82 SSTR5 (1.00) SSTR5SSTR2SSTR3SSTR4SSTR1
SCHEMBL22214904 0.82 SSTR5 (1.00) SSTR5SSTR2SSTR3SSTR4SSTR1
Seglitide SCHEMBL29691513 0.73 SSTR5 (0.56) SSTR5SSTR2SSTR3SSTR4SSTR1
Seglitide SCHEMBL25456114 0.73 SSTR5 (0.56) SSTR5SSTR2SSTR3SSTR4SSTR1
Seglitide SCHEMBL151244 0.73 SSTR5 (0.56) SSTR5SSTR2SSTR3SSTR4SSTR1
Seglitide SCHEMBL29392970 0.73 SSTR5 (0.56) SSTR5SSTR2SSTR3SSTR4SSTR1
Seglitide SCHEMBL242685 0.73 SSTR5 (0.56) SSTR5SSTR2SSTR3SSTR4SSTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1674 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124148-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY BHAMIS RES LABORATORY PVT LTD (IN) 2026-05-07 US claimed
US-20260076872-A1 POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME SIO2 MEDICAL PRODUCTS LLC (US) 2026-03-19 US claimed
US-12533321-B2 Polypeptide formulations for oral delivery Bhami's Research Laboratory, Pvt. Ltd. (IN) 2026-01-27 US claimed
EP-4602049-A1 SOS1 INHIBITORS Bayer Aktiengesellschaft (DE) 2025-08-20 EP claimed
EP-4601623-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY Bhami's Research Laboratory, Pvt. Ltd. (IN) 2025-08-20 EP claimed
US-20250242092-A1 SiOx BARRIER FOR PHARMACEUTICAL PACKAGE AND COATING PROCESS SIO2 MEDICAL PRODUCTS INC (US) 2025-07-31 US claimed
EP-4587439-A1 SULFONE-SUBSTITUTED PYRIDO[3,4-D]PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF CANCER Bayer Aktiengesellschaft (DE) 2025-07-23 EP claimed
US-20250154170-A1 FUSED PYRIMIDINES AS KRAS INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 2025-05-15 US claimed
US-12257371-B2 SiOx barrier for pharmaceutical package and coating process SIO2 MEDICAL PRODUCTS, LLC (US) 2025-03-25 US claimed
WO-2025021997-A1 NEW MAP4K1 INHIBITORS Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2025-01-30 WO claimed
US-20060009622-A1 Conjugates of therapeutic or cytotoxic agents and biologically active peptides ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE 2006-01-12 US claimed
EP-1592456-A1 CONTRAST ENHANCED X-RAY PHASE IMAGING BRACCO IMAGING S.p.A. (IT) 2005-11-09 EP claimed
CN-1649625-A Conjugates of therapeutic or cytotoxic agents and biologically active peptides UNIV TULANE (US) 2005-08-03 CN claimed
EP-1401507-A4 STABILIZATION OF RADIONUCLIDE-CONTAINING COMPOSITIONS SCHERING AG (DE) 2005-02-02 EP claimed
EP-1487493-A2 CONJUGATES OF THERAPEUTIC OR CYTOTOXIC AGENTS AND BIOLOGICALLY ACTIVE PEPTIDES The Administrators of The Tulane Educational Fund (US) 2004-12-22 EP claimed
WO-2004071535-A1 CONTRAST ENHANCED X-RAY PHASE IMAGING BRACCO IMAGING S.P.A. (IT) 2004-08-26 WO claimed
EP-1401507-A2 STABILIZATION OF RADIONUCLIDE-CONTAINING COMPOSITIONS SCHERING AKTIENGESELLSCHAFT (DE) 2004-03-31 EP claimed
WO-2003074551-A2 CONJUGATES OF THERAPEUTIC OR CYTOTOXIC AGENTS AND BIOLOGICALLY ACTIVE PEPTIDES THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2003-09-12 WO claimed
US-20020187099-A1 Stabilization of radionuclide-containing compositions BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2002-12-12 US claimed
WO-2002092005-A2 STABILIZATION OF RADIONUCLIDE-CONTAINING COMPOSITIONS SCHERING AKTIENGESELLSCHAFT (DE) 2002-11-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250154170-A1 FUSED PYRIMIDINES AS KRAS INHIBITORS KRAS, NRAS, TP53 SSTR5 4362/4885SSTR2 4568/4885SSTR3 4487/4885
US-12533321-B2 Polypeptide formulations for oral delivery PTMS, IAPP, IGF1R SSTR5 85/4885SSTR2 327/4885SSTR3 354/4885
US-20060009622-A1 Conjugates of therapeutic or cytotoxic agents and biologically active peptides MCL1, DNPEP, TP53 SSTR5 1479/4885SSTR2 2717/4885SSTR3 1311/4885
US-20260124148-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY GLP1R, TTR, IAPP SSTR5 23/4885SSTR2 75/4885SSTR3 130/4885
US-20260076872-A1 POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME MEN1, MYO1G, IL2 SSTR5 111/4885SSTR2 264/4885SSTR3 273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.