Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 4/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NRP1 | O14786 | 1/20 | 0.31 |
| ▸ | MARK3 | P27448 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL985990 | 0.67 | MEN1 (0.50) | TAAR1GAASMN1; SMN2RIPK1KDM4E | |
| SCHEMBL4565107 | 0.64 | EGFR (0.38) | MARK3 | |
| SCHEMBL987289 | 0.62 | RIPK1 (0.63) | GAASMN1; SMN2RIPK1KDM4EMEN1 | |
| SCHEMBL3026523 | 0.62 | MEN1 (0.45) | TAAR1GAASMN1; SMN2RIPK1KDM4E | |
| SCHEMBL13330544 | 0.58 | CHRNB2 (0.55) | RIPK1MEN1MAPTKMT2A | |
| SCHEMBL8846952 | 0.57 | CHRNB2 (0.49) | SMN1; SMN2RIPK1MEN1KMT2A | |
| SCHEMBL8846954 | 0.57 | CHRNB2 (0.49) | SMN1; SMN2RIPK1MEN1KMT2A | |
| SCHEMBL4019471 | 0.57 | CHRNB2 (0.49) | SMN1; SMN2RIPK1MEN1KMT2A | |
| SCHEMBL15944993 | 0.57 | LPAR2 (0.60) | GAASMN1; SMN2 | |
| SCHEMBL15947349 | 0.57 | LPAR2 (0.60) | GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009116074-A2 | SUBSTITUTED BENZIMIDAZOLES AS CANNABINOID MODULATOR | CADILA HEALTHCARE LIMITED (IN) | 2009-09-24 | — | — | WO | disclosed |