SCHEMBL4565135

SCHEMBL4565135

O=S(=O)(O)c1cc(Cl)c(S(=O)(=O)O)cc1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.39
CA2 P00918 6/20 0.39
CA12 O43570 4/20 0.39
CA4 P22748 4/20 0.39
CA6 P23280 4/20 0.39
CA5A P35218 4/20 0.39
CA7 P43166 4/20 0.39
CA9 Q16790 4/20 0.39
CA14 Q9ULX7 4/20 0.39
CA5B Q9Y2D0 4/20 0.39
CA3 P07451 3/20 0.39
CA13 Q8N1Q1 3/20 0.39
CISD1 Q9NZ45 1/20 0.39
ALDH1A1 P00352 4/20 0.38
CASP1 P29466 2/20 0.38
HSD17B10 Q99714 2/20 0.38
CYP3A4 P08684 1/20 0.38
THRB P10828 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1989758 0.97 CA1 (0.38) CA1CA2CA12CA4CA6
SCHEMBL1992615 0.97 CA1 (0.38) CA1CA2CA12CA4CA6
SCHEMBL826419 0.95 L3MBTL1 (0.44) CA1CA2CA12CA4CA6
SCHEMBL29410051 0.95 L3MBTL1 (0.44) CA1CA2CA12CA4CA6
SCHEMBL13277972 0.92 L3MBTL1 (0.42) CA1CA2CA12CA4CA6
SCHEMBL13278133 0.92 L3MBTL1 (0.42) CA1CA2CA12CA4CA6
SCHEMBL13277223 0.92 L3MBTL1 (0.42) CA1CA2CA12CA4CA6
SCHEMBL2000643 0.92 L3MBTL1 (0.42) CA1CA2CA12CA4CA6
SCHEMBL13277813 0.92 L3MBTL1 (0.42) CA1CA2CA12CA4CA6
Potassium SCHEMBL29834163 0.92 L3MBTL1 (0.42) CA1CA2CA12CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090259013-A1 LIQUID CRYSTAL POLY(PHENYLENE DISULFONIC ACIDS) CASE WESTERN RESERVE UNIVERSITY 2009-10-15 US disclosed