SCHEMBL456533

SCHEMBL456533

CC(C)NC(=S)NN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL437705 0.81 NPSR1 (0.44)
SCHEMBL11279206 0.80
SCHEMBL22747292 0.75 ALDH1A1 (0.48)
SCHEMBL10488617 0.74
SCHEMBL11301627 0.74
SCHEMBL7721260 0.73
SCHEMBL25140543 0.72
SCHEMBL10815551 0.72
SCHEMBL3077238 0.72 TAS2R38 (0.40)
SCHEMBL6683739 0.72 NPSR1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115449136-B Accelerator composition of rubber nanocomposite as well as preparation method and application thereof 浙江大学 2024-02-27 CN claimed
CN-115449136-A Accelerator composition of rubber nanocomposite and preparation method and application thereof 浙江大学 2022-12-09 CN claimed
CN-122010896-A Bicyclol derivative, pharmaceutical composition thereof, preparation method and application thereof 中国医学科学院药物研究所 2026-05-12 CN disclosed
WO-2025046420-A1 COMPOUND TARGETING EGR-1 AND USE THEREOF FOR TREATMENT OF ATOPIC DERMATITIS 주식회사 아제라메디 2025-03-06 WO disclosed
CN-115449136-B Accelerator composition of rubber nanocomposite as well as preparation method and application thereof 浙江大学 2024-02-27 CN disclosed
US-20230382947-A1 METHODS FOR PROXIMITY MEDIATED COUPLING OF A FIRST AGENT TO A SECOND AGENT UNIVERSITEIT GENT (BE) 2023-11-30 US disclosed
US-20230382947-A1 METHODS FOR PROXIMITY MEDIATED COUPLING OF A FIRST AGENT TO A SECOND AGENT UNIVERSITEIT GENT (BE) 2023-11-30 US disclosed
CN-115449136-A Accelerator composition of rubber nanocomposite and preparation method and application thereof 浙江大学 2022-12-09 CN disclosed
WO-2022079127-A1 METHODS FOR PROXIMITY MEDIATED COUPLING OF A FIRST AGENT TO A SECOND AGENT UNIVERSITEIT GENT (BE) 2022-04-21 WO disclosed
WO-2021131691-A1 COATING MATERIAL COMPOSITION, COATED METAL MATERIAL, AND METHOD FOR COATING METAL MATERIAL 日本ペイントホールディングス株式会社 2021-07-01 WO disclosed
EP-3313858-B1 METHODS FOR THE SITE-SELECTIVE COUPLING OF A FIRST AGENT TO A SECOND AGENT UNIV GENT (BE) 2019-09-25 EP disclosed
US-4871737-A 3-Amino-5-methyl-1H-pyrazole-4-carboxylic acids and esters thereof as anticonvulsants muscle relaxants and anxiolytics A. H. ROBINS COMPANY, INCORPORATED (US) 1989-10-03 US disclosed
EP-0315433-A2 3-amino-5-methyl-1H-pyrazole-4-carboxylic acids and esters thereof as anticonvulsants, muscle relaxants and anxiolytics A.H. ROBINS COMPANY, INCORPORATED (US) 1989-05-10 EP disclosed
US-4826866-A 3-amino-5-methyl-1H-pyrazole-4-carboxylic acids and esters thereof as anticonvulsants, muscle relaxants and anxiolytics A. H. ROBINS COMPANY, INCORPORATED (US) 1989-05-02 US disclosed
US-4492793-A Process for the production of 2-amino-5-mercapto-1,3,4-thiadiazole DEGUSSA AKTIENGESELLSCHAFT (DE) 1985-01-08 US disclosed
US-4309426-A Muscle-relaxant 1,3,4-thiadiazin-2-amines RICHARDSON-MERRELL INC. (US) 1982-01-05 US disclosed
US-4272532-A SEDATIVES RICHARDSON-MERRELL INC. (US) 1981-06-09 US disclosed
US-4252962-A Process for producing 2-amino or selected 2-(substituted)amino-5-mercapto-1,3,4-thiadiazole compounds OLIN CORPORATION (US) 1981-02-24 US disclosed
US-4026903-A ANTIMICROBIAL AMERICAN CYANAMID COMPANY (US) 1977-05-31 US disclosed
US-3940411-A MICROBIOCIDES AMERICAN CYANAMID COMPANY (US) 1976-02-24 US disclosed