Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4565518 | 0.99 | HRH3 (0.57) | HRH3ITGB3ITGA2BLTA4H | |
| SCHEMBL5100244 | 0.85 | HRH3 (0.69) | HRH3 | |
| SCHEMBL3653090 | 0.83 | HRH3 (0.64) | HRH3 | |
| Hydrochloric Acid SCHEMBL4535011 | 0.82 | HRH3 (0.62) | HRH3 | |
| SCHEMBL4565153 | 0.82 | HRH3 (0.58) | HRH3 | |
| SCHEMBL6071260 | 0.80 | HRH3 (0.72) | HRH3 | |
| SCHEMBL8420465 | 0.80 | HRH3 (0.59) | HRH3 | |
| SCHEMBL19574597 | 0.80 | ITGB3 (0.55) | ITGB3ITGA2B | |
| SCHEMBL3693926 | 0.79 | DRD3 (0.56) | — | |
| SCHEMBL3649879 | 0.77 | HRH3 (0.74) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069300-A1 | ISOQUINOLINYL AND ISOINDOLINYL DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069300-A1 | ISOQUINOLINYL AND ISOINDOLINYL DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | HRH4, HRH3, HRH2 | HRH3 2/4885ITGB3 3243/4885ITGA2B 4322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.