Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 6/20 | 0.47 |
| ▸ | ERN1 | O75460 | 13/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470248 | 0.87 | ERN1 (0.48) | TTKERN1 | |
| SCHEMBL470005 | 0.86 | TTK (0.56) | TTKMKNK1 | |
| SCHEMBL459313 | 0.85 | TTK (0.47) | TTKERN1 | |
| SCHEMBL458070 | 0.83 | ERN1 (0.44) | TTKERN1 | |
| SCHEMBL470209 | 0.82 | TTK (0.56) | TTKERN1MKNK1 | |
| SCHEMBL10279180 | 0.78 | TTK (0.56) | TTKERN1MKNK1 | |
| SCHEMBL104538 | 0.77 | TTK (0.77) | TTK | |
| SCHEMBL458814 | 0.77 | TTK (0.52) | TTKERN1 | |
| SCHEMBL10279181 | 0.77 | TTK (0.59) | TTKERN1MKNK1 | |
| SCHEMBL10279183 | 0.77 | TTK (0.58) | TTKMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9255100-B2 | Substituted imidazopyridazines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-09 | — | — | US | disclosed |
| EP-2614063-B1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER IP GMBH (DE) | 2016-01-13 | — | — | EP | disclosed |
| EP-2614063-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | Bayer Intellectual Property GmbH (DE) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |