Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 10/20 | 0.56 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.46 |
| ▸ | FYN | P06241 | 8/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470169 | 0.87 | TTK (0.45) | TTKMKNK1FYN | |
| SCHEMBL456540 | 0.86 | TTK (0.47) | TTKMKNK1 | |
| SCHEMBL459155 | 0.81 | TTK (0.56) | TTKMKNK1FYN | |
| SCHEMBL456264 | 0.79 | TTK (0.51) | TTKFYN | |
| SCHEMBL456974 | 0.79 | TTK (0.71) | TTKMKNK1 | |
| SCHEMBL17590075 | 0.79 | TTK (0.87) | TTK | |
| SCHEMBL458383 | 0.79 | TTK (0.55) | TTKMKNK1 | |
| SCHEMBL469994 | 0.78 | FYN (0.47) | TTKMKNK1FYN | |
| SCHEMBL470122 | 0.74 | TTK (0.93) | TTK | |
| SCHEMBL459286 | 0.74 | TTK (0.39) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9255100-B2 | Substituted imidazopyridazines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-09 | — | — | US | disclosed |
| EP-2614063-B1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER IP GMBH (DE) | 2016-01-13 | — | — | EP | disclosed |
| EP-2614063-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | Bayer Intellectual Property GmbH (DE) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |