SCHEMBL470248

SCHEMBL470248

CC(C)(C)CNc1cc(Cl)nn2c(-c3ccc(C4OCCO4)cc3)cnc12

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 15/20 0.48
TTK P33981 5/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL459313 0.92 TTK (0.47) ERN1TTK
SCHEMBL456540 0.87 TTK (0.47) ERN1TTK
SCHEMBL458070 0.85 ERN1 (0.44) ERN1TTK
SCHEMBL470247 0.82 TTK (0.53) ERN1TTK
SCHEMBL456264 0.78 TTK (0.51) ERN1TTK
SCHEMBL469994 0.78 FYN (0.47) TTK
SCHEMBL470169 0.78 TTK (0.45) TTK
SCHEMBL457290 0.76 TTK (0.43) ERN1TTK
SCHEMBL456811 0.76 TTK (0.53) ERN1TTK
SCHEMBL456263 0.75 TTK (0.45) TTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012032031-A1 SUBSTITUTED IMIDAZOPYRIDAZINES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2012-03-15 WO disclosed