Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3582993 | 0.90 | QPCT (0.49) | QPCTLMNAMDM4MDM2QPCTL | |
| SCHEMBL3589146 | 0.90 | QPCT (0.49) | QPCTLMNAMDM4MDM2QPCTL | |
| SCHEMBL3583000 | 0.90 | QPCT (0.49) | QPCTLMNAMDM4MDM2QPCTL | |
| SCHEMBL9843082 | 0.77 | QPCT (0.57) | QPCTLMNAMEN1KMT2A | |
| SCHEMBL11415790 | 0.75 | QPCT (0.54) | QPCTMEN1KMT2A | |
| SCHEMBL11405716 | 0.73 | QPCT (0.52) | QPCTMEN1POLBKMT2A | |
| SCHEMBL11281134 | 0.73 | QPCT (0.52) | QPCTLMNAQPCTL | |
| SCHEMBL11659545 | 0.72 | MDM2 (0.56) | LMNAMDM4MDM2MEN1KMT2A | |
| SCHEMBL11420791 | 0.71 | QPCT (0.50) | QPCTQPCTL | |
| SCHEMBL7950899 | 0.69 | CYP1A2 (0.43) | QPCTLMNAMDM2MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | disclosed |