Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566190 | 0.88 | LMNA (0.48) | QPCTLMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL11415790 | 0.84 | QPCT (0.54) | QPCTALDH1A1KDM4EGAATDP1 | |
| SCHEMBL11281134 | 0.82 | QPCT (0.52) | QPCTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11405716 | 0.82 | QPCT (0.52) | QPCTALDH1A1KDM4EGAATDP1 | |
| SCHEMBL3583000 | 0.81 | QPCT (0.49) | QPCTLMNAALDH1A1 | |
| SCHEMBL3589146 | 0.81 | QPCT (0.49) | QPCTLMNAALDH1A1 | |
| SCHEMBL3582993 | 0.81 | QPCT (0.49) | QPCTLMNAALDH1A1 | |
| SCHEMBL11420791 | 0.80 | QPCT (0.50) | QPCTALDH1A1KDM4EGAATDP1 | |
| SCHEMBL11497150 | 0.78 | QPCT (0.48) | QPCTLMNAALDH1A1KDM4EGAA | |
| SCHEMBL4565683 | 0.77 | QPCT (0.48) | QPCTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442448-A2 | Heterocyclic carboxylic acids and esters | Bristol-Myers Squibb Company (US) | 1991-08-21 | — | — | EP | disclosed |
| US-4970225-A | ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1990-11-13 | — | — | US | disclosed |
| US-4281009-A | SEDATIVES, ANALGESICS, ANTIULCER AGENTS, A HYPNOTIC AND ANTIHYPERTENSIVE AGENTS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1981-07-28 | — | — | US | disclosed |
| EP-0006407-A1 | Hydantoin derivatives, their preparation and pharmaceutical compositions containing them | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1980-01-09 | — | — | EP | disclosed |