Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.31 |
| ▸ | DCK | P27707 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL610510 | 0.67 | AHR (0.44) | ALDH1A1 | |
| SCHEMBL4538578 | 0.61 | FASN (0.50) | ALOX5APFEN1TRPV4DCKALDH1A1 | |
| SCHEMBL2463985 | 0.58 | AHR (0.53) | — | |
| SCHEMBL31554923 | 0.57 | ACLY (0.35) | ALOX5APFEN1TRPV4 | |
| SCHEMBL3378723 | 0.55 | KIT (0.45) | ALDH1A1 | |
| SCHEMBL2663826 | 0.55 | KCNH2 (0.43) | ALOX5APFEN1ALDH1A1 | |
| SCHEMBL2458495 | 0.54 | AHR (0.67) | ALDH1A1 | |
| SCHEMBL4500062 | 0.54 | SCN9A (0.52) | — | |
| SCHEMBL10576789 | 0.53 | SRD5A2 (0.43) | — | |
| SCHEMBL4424115 | 0.53 | RIPK1 (0.40) | ALOX5APFEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2637660-A1 | FATTY ACID SYNTHASE INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012064642-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2012-05-18 | — | — | WO | disclosed |