Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 18/20 | 0.51 |
| ▸ | BRAF | P15056 | 17/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | TEK | Q02763 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4419811 | 0.93 | TEK (0.46) | RAF1BRAFCNR1TEK | |
| SCHEMBL14473020 | 0.88 | RAF1 (0.53) | RAF1BRAF | |
| SCHEMBL5593311 | 0.88 | RAF1 (0.46) | RAF1BRAF | |
| SCHEMBL4417829 | 0.84 | TEK (0.45) | RAF1BRAFTEK | |
| SCHEMBL4408593 | 0.83 | TEK (0.43) | RAF1BRAFTEK | |
| SCHEMBL5603042 | 0.82 | TEK (0.44) | RAF1BRAFTEK | |
| SCHEMBL5593352 | 0.82 | RAF1 (0.41) | RAF1BRAF | |
| SCHEMBL5593020 | 0.82 | RAB9A (0.49) | RAF1BRAFTEK | |
| SCHEMBL4412693 | 0.81 | RAF1 (0.49) | RAF1BRAF | |
| SCHEMBL4417914 | 0.81 | TEK (0.43) | RAF1BRAFTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035005-A2 | THERAPY USING CYTOKINE INHIBITORS | Kemia, INC. (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007146712-A2 | THERAPY USING CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |