Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 14/20 | 0.41 |
| ▸ | BRAF | P15056 | 14/20 | 0.41 |
| ▸ | CSF1R | P07333 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593311 | 0.95 | RAF1 (0.46) | RAF1BRAFCSF1R | |
| SCHEMBL4419811 | 0.89 | TEK (0.46) | RAF1BRAF | |
| SCHEMBL4412596 | 0.88 | ACKR3 (0.43) | RAF1BRAFCSF1RMAPK14NPC1 | |
| SCHEMBL4409531 | 0.88 | RAF1 (0.42) | RAF1BRAFCSF1R | |
| SCHEMBL4409551 | 0.87 | RAF1 (0.43) | RAF1BRAFCSF1R | |
| SCHEMBL4565287 | 0.85 | RAB9A (0.47) | RAF1BRAFMAPK14NPC1RAB9A | |
| SCHEMBL4416214 | 0.84 | MAPK14 (0.43) | RAF1BRAFMAPK14NPC1RAB9A | |
| SCHEMBL4415069 | 0.84 | MAPK14 (0.47) | RAF1BRAFMAPK14NPC1 | |
| SCHEMBL4418552 | 0.83 | MAPK14 (0.44) | RAF1BRAFMAPK14NPC1RAB9A | |
| SCHEMBL4408497 | 0.83 | MAPK14 (0.48) | RAF1BRAFMAPK14NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |