⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24638320 | 0.71 | — | — | |
| SCHEMBL27867439 | 0.71 | — | — | |
| SCHEMBL25423572 | 0.69 | MGAM (0.32) | — | |
| SCHEMBL11323708 | 0.67 | — | — | |
| SCHEMBL17520439 | 0.67 | — | — | |
| SCHEMBL3592185 | 0.66 | — | — | |
| SCHEMBL28309799 | 0.65 | IRAK4 (0.36) | — | |
| SCHEMBL22861810 | 0.65 | GABRA1 (0.33) | — | |
| SCHEMBL22380047 | 0.65 | — | — | |
| SCHEMBL25948835 | 0.63 | SLC6A2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134721-A1 | ANTIMICROBIAL HETEROCYCLIC COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | Micurx Pharmaceuticals, Inc. (US) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008108988-A1 | ANTIMICROBIAL HETEROCYCLIC COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |