Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1260945 | 0.78 | SCN9A (0.65) | SCN9ASCN5ACNR2ALDH1A1NPSR1 | |
| SCHEMBL196105 | 0.77 | SCN9A (0.50) | SCN9ASCN5ACNR2ALDH1A1NPSR1 | |
| SCHEMBL899454 | 0.77 | SCN9A (0.64) | SCN9ASCN5ACNR2ALDH1A1NPSR1 | |
| SCHEMBL4830054 | 0.74 | SCN9A (0.49) | SCN9ASCN5ACNR2ALDH1A1NPSR1 | |
| SCHEMBL4831650 | 0.73 | HRH2 (0.48) | SCN9ASCN5ACNR2 | |
| SCHEMBL4822336 | 0.73 | CNR2 (0.47) | SCN9ASCN5ACNR2ALDH1A1NPSR1 | |
| SCHEMBL13577960 | 0.71 | SCN9A (0.46) | SCN9ASCN5ACNR2ALDH1A1NPSR1 | |
| SCHEMBL13577940 | 0.71 | HPGD (0.44) | SCN9ASCN5ACNR2ALDH1A1NPSR1 | |
| SCHEMBL4827022 | 0.70 | SCN9A (0.46) | SCN9ASCN5ACNR2ALDH1A1NPSR1 | |
| SCHEMBL772052 | 0.70 | HRH2 (0.44) | SCN9ASCN5ACNR2ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121707-A1 | ANTIVIRAL INDOLES | Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. (IT) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008075103-A1 | ANTIVIRAL INDOLES | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2008-06-26 | — | — | WO | disclosed |