Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 6/20 | 0.34 |
| ▸ | CA2 | P00918 | 6/20 | 0.34 |
| ▸ | CA9 | Q16790 | 6/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6336308 | 0.90 | THRB (0.35) | PRSS1PRSS2PRSS3MEN1KMT2A | |
| SCHEMBL7455857 | 0.87 | THRB (0.40) | PRSS1PRSS2PRSS3MEN1KMT2A | |
| SCHEMBL10706187 | 0.87 | THRB (0.40) | PRSS1PRSS2PRSS3MEN1KMT2A | |
| SCHEMBL6331643 | 0.87 | THRB (0.40) | PRSS1PRSS2PRSS3MEN1KMT2A | |
| SCHEMBL7541647 | 0.87 | PRSS1 (0.36) | PRSS1PRSS2PRSS3MEN1KMT2A | |
| SCHEMBL3986271 | 0.81 | — | — | |
| SCHEMBL5933287 | 0.81 | — | — | |
| SCHEMBL10864549 | 0.81 | — | — | |
| SCHEMBL5932707 | 0.79 | THRB (0.42) | MEN1KMT2ANAAATHRBTSHR | |
| SCHEMBL5932320 | 0.79 | THRB (0.42) | MEN1KMT2ANAAATHRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069240-A2 | BOOTSTRAP SYNTHESIS OF BORANES | Los Alamos National Security, LLC (US) | 2009-06-17 | — | — | EP | claimed |
| US-20080175781-A1 | Bootstrap synthesis of boranes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-07-24 | — | — | US | claimed |
| WO-2008039312-A2 | BOOTSTRAP SYNTHESIS OF BORANES | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2008-04-03 | — | — | WO | claimed |
| EP-2069240-A2 | BOOTSTRAP SYNTHESIS OF BORANES | Los Alamos National Security, LLC (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-2069240-A2 | BOOTSTRAP SYNTHESIS OF BORANES | Los Alamos National Security, LLC (US) | 2009-06-17 | — | — | EP | disclosed |
| US-20080175781-A1 | Bootstrap synthesis of boranes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-07-24 | — | — | US | disclosed |
| US-20080175781-A1 | Bootstrap synthesis of boranes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-07-24 | — | — | US | disclosed |
| WO-2008039312-A3 | BOOTSTRAP SYNTHESIS OF BORANES | LOS ALAMOS NAT SECURITY LLC (US) | 2008-05-08 | — | — | WO | disclosed |
| WO-2008039312-A2 | BOOTSTRAP SYNTHESIS OF BORANES | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2008-04-03 | — | — | WO | disclosed |
| WO-2008039312-A2 | BOOTSTRAP SYNTHESIS OF BORANES | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2008-04-03 | — | — | WO | disclosed |
| EP-1115695-A1 | (R)-CHIRAL HALOGENATED 1-SUBSTITUTEDAMINO-(N+1)-ALKANOLS USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | Monsanto Company (US) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018724-A1 | (R)-CHIRAL HALOGENATED 1-SUBSTITUTEDAMINO-(n+1)-ALKANOLS USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | MONSANTO COMPANY (US) | 2000-04-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080175781-A1 | Bootstrap synthesis of boranes | BCL2L13, BCL2L11, BCL2L2 | PRSS1 3521/4885PRSS2 2121/4885PRSS3 1895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.