⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6336308 | 0.92 | THRB (0.35) | — | |
| SCHEMBL6331643 | 0.90 | THRB (0.40) | — | |
| SCHEMBL10706187 | 0.90 | THRB (0.40) | — | |
| SCHEMBL7455857 | 0.90 | THRB (0.40) | — | |
| SCHEMBL9634416 | 0.89 | ADRB2 (0.39) | — | |
| SCHEMBL4651146 | 0.82 | — | — | |
| SCHEMBL4565912 | 0.81 | PRSS1 (0.38) | — | |
| SCHEMBL5932297 | 0.80 | TSHR (0.39) | — | |
| SCHEMBL1220263 | 0.80 | — | — | |
| SCHEMBL10864549 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541478-B2 | Coumarin derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-02 | — | — | US | disclosed |
| US-20070197636-A1 | Coumarin Derivative And Use Thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-08-23 | — | — | US | disclosed |
| US-20070179154-A1 | Coumarin derivatives, process for their production and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-08-02 | — | — | US | disclosed |
| EP-1720850-A1 | COUMARIN DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2006-11-15 | — | — | EP | disclosed |
| US-20060035865-A1 | Lipid-rich plaque regressing agents | TERASHITA ZEN-ICHI | 2006-02-16 | — | — | US | disclosed |
| US-6974806-B2 | Lipid-rich plaque inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-12-13 | — | — | US | disclosed |
| WO-2005082879-A1 | COUMARIN DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-09-09 | — | — | WO | disclosed |
| US-20050020634-A1 | Coumarin derivatives, process for their production and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-01-27 | — | — | US | disclosed |
| EP-1471064-A1 | COUMARIN DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-20030232809-A1 | Lipid-rich plaque inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-12-18 | — | — | US | disclosed |
| EP-1302470-A1 | LIPID-RICH PLAQUE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 2003-04-16 | — | — | EP | disclosed |
| US-4895981-A | Using ultraviolet absorber | CIBA-GEIGY CORPORATION (US) | 1990-01-23 | — | — | US | disclosed |
| US-4732615-A | RECORDING | TAOKA CHEMICAL CO., LTD. (JP) | 1988-03-22 | — | — | US | disclosed |
| EP-0196901-A2 | Copper phthalocyanine compound and aqueous ink composition comprising the same | TAOKA CHEMICAL CO., LTD (JP) | 1986-10-08 | — | — | EP | disclosed |
| EP-0173857-A1 | Fungicidal agent based on phosphoryloximinoacetamide | BAYER AG (DE) | 1986-03-12 | — | — | EP | disclosed |