Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.85 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.85 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.85 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.85 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.85 |
| ▸ | USP2 | O75604 | 1/20 | 0.85 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.85 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.85 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.85 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.85 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.85 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.85 |
| ▸ | ACE | P12821 | 1/20 | 0.85 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.85 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.85 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.85 |
| ▸ | PDE4A | P27815 | 1/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29377244 | 1.00 | PPARG (0.85) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| SCHEMBL28397323 | 0.94 | PPARG (0.84) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| SCHEMBL6080037 | 0.92 | AGTR1 (0.75) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| Telmisartan SCHEMBL29356790 | 0.92 | AGTR1 (1.00) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| Telmisartan SCHEMBL29414101 | 0.92 | AGTR1 (1.00) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| Telmisartan SCHEMBL2122886 | 0.92 | AGTR1 (1.00) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| Telmisartan SCHEMBL29691699 | 0.92 | AGTR1 (1.00) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| Telmisartan SCHEMBL4464 | 0.92 | AGTR1 (1.00) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| Telmisartan SCHEMBL3384004 | 0.91 | AGTR1 (0.98) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| Telmisartan SCHEMBL998659 | 0.91 | AGTR1 (0.98) | PPARGAGTR1AGTR2KDM4EABCC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111053910-A | Composition comprising fatty acid or derivative thereof and disubstituted biphenyl derivative | 黄泳华 | 2020-04-24 | — | — | CN | claimed |
| EP-1393722-A2 | Use of angiotensin II subtype 1 (AT1) antagonists for the manufacture of a medicament in the treatment of premenstrual syndrome | DePadova, Anthony S. (US) | 2004-03-03 | — | — | EP | claimed |
| CN-116675648-A | Preparation method of telmisartan | 迪嘉药业集团股份有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-114573513-B | Synthesis method of telmisartan intermediate | 济南大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-114573513-A | Synthesis method of telmisartan intermediate | 济南大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-110934848-B | Telmisartan capsule and preparation method thereof | 江西杏林白马药业股份有限公司 | 2022-02-15 | — | — | CN | disclosed |
| CN-111053910-A | Composition comprising fatty acid or derivative thereof and disubstituted biphenyl derivative | 黄泳华 | 2020-04-24 | — | — | CN | disclosed |
| CN-110934848-A | Telmisartan capsule and preparation method thereof | 江西杏林白马药业有限公司 | 2020-03-31 | — | — | CN | disclosed |
| EP-2046756-A2 | PREPARATION OF TELMISARTAN SALTS | Krka Tovarna Zdravil, D.D., Novo Mesto (SI) | 2009-04-15 | — | — | EP | disclosed |
| EP-1912975-A1 | A PROCESS FOR THE PREPARATION OF TELMISARTAN | Matrix Laboratories Ltd (IN) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007147889-A2 | PREPARATION OF TELMISARTAN SALTS | KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) | 2007-12-27 | — | — | WO | disclosed |
| WO-2007028524-A2 | USE OF A DERIVATIVE OF IMIDAZOLE FOR THE TREATMENT OF LEUKOTRIENE RELATED DISORDERS | PROUS INSTITUTE FOR BIOMEDICAL RESEARCH S.A. (ES) | 2007-03-15 | — | — | WO | disclosed |
| WO-2007010558-A1 | A PROCESS FOR THE PREPARATION OF TELMISARTAN | MATRIX LABORATORIES LIMITED (IN) | 2007-01-25 | — | — | WO | disclosed |
| EP-1313468-A2 | PHARMACEUTICAL COMBINATION OF ANGIOTENSIN II ANTAGONISTS AND ACE INHIBITORS | Boehringer Ingelheim Pharma KG (DE) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002015891-A2 | PHARMACEUTICAL COMBINATION OF ANGIOTENSIN II ANTAGONISTS AND ACE INHIBITORS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-02-28 | — | — | WO | disclosed |