SCHEMBL4566012

SCHEMBL4566012

CCCCCCC(CN)CCCCC

nearest known ligand 0.64

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.64
TDP1 Q9NUW8 1/20 0.64
LMNA P02545 1/20 0.56
OPRM1 P35372 1/20 0.48
DNM1 Q05193 8/20 0.48
TSHR P16473 2/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
EPHX1 P07099 1/20 0.48
THRB P10828 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10383392 1.00 ALDH1A1 (0.64) ALDH1A1TDP1LMNAOPRM1DNM1
SCHEMBL11042224 1.00 ALDH1A1 (0.64) ALDH1A1TDP1LMNAOPRM1DNM1
SCHEMBL20495959 1.00 ALDH1A1 (0.64) ALDH1A1TDP1LMNAOPRM1DNM1
SCHEMBL14436836 1.00 ALDH1A1 (0.64) ALDH1A1TDP1LMNAOPRM1DNM1
SCHEMBL24684882 1.00 ALDH1A1 (0.64) ALDH1A1TDP1LMNAOPRM1DNM1
SCHEMBL22658086 1.00 ALDH1A1 (0.64) ALDH1A1TDP1LMNAOPRM1DNM1
SCHEMBL24200454 1.00 ALDH1A1 (0.64) ALDH1A1TDP1LMNAOPRM1DNM1
SCHEMBL22342116 1.00 ALDH1A1 (0.64) ALDH1A1TDP1LMNAOPRM1DNM1
SCHEMBL22766465 1.00 ALDH1A1 (0.64) ALDH1A1TDP1LMNAOPRM1DNM1
SCHEMBL20495968 1.00 ALDH1A1 (0.64) ALDH1A1TDP1LMNAOPRM1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2125031-A2 LIPIDS AND LIPID ASSEMBLIES COMPRISING TRANSFECTION ENHANCER ELEMENTS Novosom AG (DE) 2009-12-02 EP claimed
US-20080306153-A1 Lipids and lipid assemblies comprising transfection enhancer elements CEQUENT PHARMACEUTICALS, INC. 2008-12-11 US claimed
EP-1938843-A1 Lipids and lipid assemblies comrising transfection enhancer elements Novosom AG (DE) 2008-07-02 EP claimed
WO-2008074487-A2 LIPIDS AND LIPID ASSEMBLIES COMPRISING TRANSFECTION ENHANCER ELEMENTS NOVOSOM AG (DE) 2008-06-26 WO claimed
US-20080145413-A1 Lipids and lipid assemblies comprising transfection enhancer elements MARINA BIOTECH, INC. 2008-06-19 US claimed
US-7189705-B2 Methods of enhancing SPLP-mediated transfection using endosomal membrane destabilizers THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2007-03-13 US claimed
CN-117624029-A Arylpyridine or arylpiperidine derivative or salt thereof, synthesis and application and medicine 赣江中药创新中心 2024-03-01 CN disclosed
CN-115215800-B Dibenzocyclyl-cyclic amino ether derivative or salt, and preparation method and application thereof 赣江中药创新中心 2023-07-18 CN disclosed
CN-115215800-A Dibenzocyclyl-cyclic amino ether derivative or salt and preparation method and application thereof 赣江中药创新中心 2022-10-21 CN disclosed
US-9618653-B2 Microelectronic environmental sensing module STMICROELECTRONICS PTE LTD. (SG) 2017-04-11 US disclosed
US-8193246-B2 Lipids and lipid assemblies comprising transfection enhancer elements MARINA BIOTECH, INC. (US) 2012-06-05 US disclosed
WO-2011158257-A1 PREPARATION PROCESS OF FESOTERODINE AND INTERMEDIATES PANACEA BIOTEC LTD (IN) 2011-12-22 WO disclosed
US-7723345-B2 Multicyclic amino acid derivatives and methods of their use LEXICON PHARMACEUTICALS, INC. (US) 2010-05-25 US disclosed
EP-1019358-B1 3,3-DIARYLPROPYLAMINES , THEIR USE AND PREPARATION PHARMACIA AB (SE) 2003-05-07 EP disclosed
US-6313132-B1 FOR THERAPY OF URINARY INCONTINENCE, ACETYLCHOLINE-MEDIATED DISORDER PHARMACIA AB (SE) 2001-11-06 US disclosed
US-6313132-B1 FOR THERAPY OF URINARY INCONTINENCE, ACETYLCHOLINE-MEDIATED DISORDER PHARMACIA AB (SE) 2001-11-06 US disclosed
EP-1019358-A1 NOVEL COMPOUNDS, THEIR USE AND PREPARATION Pharmacia & Upjohn AB (SE) 2000-07-19 EP disclosed
WO-1998043942-A1 NOVEL COMPOUNDS, THEIR USE AND PREPARATION PHARMACIA & UPJOHN AB (SE) 1998-10-08 WO disclosed
US-4098890-A METHOD FOR TREATING ARRHYTHMIA ELI LILLY AND COMPANY (US) 1978-07-04 US disclosed
US-3987201-A ARYL AMINES ELI LILLY AND COMPANY (US) 1976-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080145413-A1 Lipids and lipid assemblies comprising transfection enhancer elements HNRNPH3, SREBF2, PHOSPHO1 ALDH1A1 4867/4885TDP1 1475/4885LMNA 446/4885
US-20080306153-A1 Lipids and lipid assemblies comprising transfection enhancer elements SREBF1, SREBF2, ELOVL1 ALDH1A1 3614/4885TDP1 1587/4885LMNA 513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.