Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL931964 | 0.74 | OXTR (0.34) | CACNA1HHSP90AA1HSP90AB1GAA | |
| SCHEMBL8931481 | 0.70 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1 | |
| SCHEMBL12203091 | 0.67 | TUBB4A (0.36) | HSP90AA1HSP90AB1 | |
| SCHEMBL14328376 | 0.67 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1 | |
| SCHEMBL18430743 | 0.67 | POLB (0.46) | POLBGAAGFER | |
| SCHEMBL8931493 | 0.63 | CA9 (0.40) | CACNA1HPOLBGAAGFER | |
| SCHEMBL12832377 | 0.63 | CA9 (0.40) | CACNA1HPOLBGAAGFER | |
| SCHEMBL8931486 | 0.62 | CHRNA7 (0.36) | CACNA1HPOLB | |
| SCHEMBL8931491 | 0.62 | KMT2A (0.46) | POLB | |
| SCHEMBL419166 | 0.61 | HSP90AA1 (0.53) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026797-A2 | METHOD FOR TREATING NON-HODGKIN'S LYMPHOMA | Synta Pharmaceuticals Corporation (US) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007140002-A2 | METHOD FOR TREATING NON-HODGKIN'S LYMPHOMA | SYNTA PHARMACEUTICALS CORP. (US) | 2007-12-06 | — | — | WO | disclosed |