Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4566262 | 0.79 | TSHR (0.35) | POLBTSHRMAPK1MEN1KMT2A | |
| SCHEMBL7721500 | 0.67 | POLB (0.63) | POLBTSHRMAPK1MEN1KMT2A | |
| SCHEMBL13885373 | 0.66 | GSK3B (0.32) | TSHRMAPK1MEN1KMT2AMAPT | |
| SCHEMBL20088736 | 0.64 | POLB (0.41) | POLBTSHRMAPK1MEN1KMT2A | |
| SCHEMBL102461 | 0.64 | POLB (0.51) | POLBTSHRMAPK1MEN1KMT2A | |
| SCHEMBL30039598 | 0.63 | POLB (0.38) | POLBTSHRMAPK1MEN1KMT2A | |
| SCHEMBL4091067 | 0.63 | TSHR (0.37) | POLBTSHRMAPK1MEN1KMT2A | |
| SCHEMBL4092944 | 0.62 | HTR2A (0.33) | TSHRMEN1KMT2AMAPT | |
| SCHEMBL7569210 | 0.61 | KDM4E (0.38) | TSHRMEN1KMT2AMAPT | |
| SCHEMBL3839029 | 0.61 | KDM4E (0.49) | TSHRMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009055674-A1 | PYRROLOPYRIMIDINE ALKYNYL COMPOUNDS AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-04-30 | — | — | WO | disclosed |