Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21725642 | 0.81 | HTR2A (0.36) | HTR2AEEDKDM4EMEN1ALDH1A1 | |
| SCHEMBL4085111 | 0.71 | IMPDH2 (0.35) | TSHR | |
| SCHEMBL13885373 | 0.71 | GSK3B (0.32) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL13180801 | 0.70 | SLC6A2 (0.43) | HTR2AEEDMEN1ALDH1A1CYP1A2 | |
| SCHEMBL13885101 | 0.69 | BRAF (0.34) | — | |
| SCHEMBL4094828 | 0.69 | CA12 (0.35) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL13885222 | 0.69 | HRH4 (0.33) | HTR2A | |
| SCHEMBL4082423 | 0.68 | SLC6A2 (0.44) | HTR2AEED | |
| SCHEMBL21725644 | 0.68 | SLC6A2 (0.44) | HTR2AEEDMEN1ALDH1A1CYP1A2 | |
| SCHEMBL14685790 | 0.68 | SLC6A2 (0.46) | HTR2AEED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009055674-A1 | PYRROLOPYRIMIDINE ALKYNYL COMPOUNDS AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-04-30 | — | — | WO | disclosed |